Flow-induced Shear Stress Confers Resistance to Carboplatin in an Adherent Three-Dimensional Model for Ovarian Cancer: A Role for EGFR-Targeted Photoimmunotherapy Informed by Physical Stress

A key reason for the persistently grim statistics associated with metastatic ovarian cancer is resistance to conventional agents, including platinum-based chemotherapies. A major source of treatment failure is the high degree of genetic and molecular heterogeneity, which results from significant und...

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Veröffentlicht in:	Journal of clinical medicine 2020-03, Vol.9 (4), p.924
Hauptverfasser:	Nath, Shubhankar, Pigula, Michael, Khan, Amjad P, Hanna, William, Ruhi, Mustafa Kemal, Dehkordy, Farzaneh Mahmoodpoor, Pushpavanam, Karthik, Rege, Kaushal, Moore, Kaitlin, Tsujita, Yujiro, Conrad, Christina, Inci, Fatih, Carmen, Marcela G Del, Franco, Walfre, Celli, Jonathan P, Demirci, Utkan, Hasan, Tayyaba, Huang, Huang-Chiao, Rizvi, Imran
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Ascites Cancer research Cancer therapies Chemotherapy Clinical medicine Growth factors Kinases Metastasis Ovarian cancer Proteins Shear stress Surgery Tumors
Online-Zugang:	Volltext
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