Prognostic stratification of clinical and molecular epithelioid hemangioendothelioma subsets

Epithelioid hemangioendothelioma is a low-grade malignant vascular tumor with an intermediate clinical behavior between benign hemangiomas and high-grade angiosarcomas. Pathologic or molecular factors to predict this clinical heterogeneity are not well defined. A WWTR1-CAMTA1 fusion is present in mo...

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Veröffentlicht in:	Modern pathology 2020-04, Vol.33 (4), p.591-602
Hauptverfasser:	Rosenbaum, Evan, Jadeja, Bhumika, Xu, Bin, Zhang, Lei, Agaram, Narasimhan P., Travis, William, Singer, Samuel, Tap, William D., Antonescu, Cristina R.
Format:	Artikel
Sprache:	eng
Schlagworte:	14/32 45/91 631/67/1798 692/420/755 Adaptor Proteins, Signal Transducing - genetics Adolescent Adult Aged Aged, 80 and over Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - genetics Biomarkers, Tumor - genetics Calcium-Binding Proteins - genetics DNA sequencing Female Gene Fusion Genetic Predisposition to Disease Hemangioendothelioma, Epithelioid - genetics Hemangioendothelioma, Epithelioid - mortality Hemangioendothelioma, Epithelioid - pathology Hemangioendothelioma, Epithelioid - therapy Hemangioma Humans Laboratory Medicine Lymph nodes Lymphatic system Male Medical prognosis Medicine Medicine & Public Health Metastases Metastasis Middle Aged Neoplasm Grading Pathology Patients Phenotype Retrospective Studies Surgery Survival Time Factors Trans-Activators - genetics Transcription Factors - genetics Transcriptional Coactivator with PDZ-Binding Motif Proteins Tumors Vein & artery diseases YAP-Signaling Proteins Yes-associated protein Young Adult
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