COVID-19 (SARS-CoV-2) and the Heart – An Ominous Association
Coronavirus disease 2019 (COVID-19) is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Cardiovascular manifestations of COVID-19 are diverse and complex and include acute coronary syndrome, myocarditis masquerading as ST-segment elevation myocardial infa...
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Veröffentlicht in: | Cardiovascular revascularization medicine 2020-08, Vol.21 (8), p.946-949 |
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creator | Khalid, Nauman Chen, Yuefeng Case, Brian C. Shlofmitz, Evan Wermers, Jason P. Rogers, Toby Ben-Dor, Itsik Waksman, Ron |
description | Coronavirus disease 2019 (COVID-19) is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Cardiovascular manifestations of COVID-19 are diverse and complex and include acute coronary syndrome, myocarditis masquerading as ST-segment elevation myocardial infarction, pericarditis and pericardial effusion. We present 2 cases of COVID-19 infection with myocardial involvement with distinct mechanistic pathways and outcomes. Important decision strategies such as the timing of cardiac catheterization (when indicated) and requirement of early hemodynamic support in critically ill patients are discussed.
•Cardiovascular manifestations of COVID-19 are diverse and complex.•We present 2 cases of COVID-19 infection with myocardial involvement.•We discuss strategies such as timing of cardiac catheterization (when indicated). |
doi_str_mv | 10.1016/j.carrev.2020.05.009 |
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•Cardiovascular manifestations of COVID-19 are diverse and complex.•We present 2 cases of COVID-19 infection with myocardial involvement.•We discuss strategies such as timing of cardiac catheterization (when indicated).</description><identifier>ISSN: 1553-8389</identifier><identifier>EISSN: 1878-0938</identifier><identifier>DOI: 10.1016/j.carrev.2020.05.009</identifier><identifier>PMID: 32423791</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Acute coronary syndrome ; Adult ; Betacoronavirus ; Clinical ; Complications ; Coronary Angiography ; Coronavirus Infections - complications ; Coronavirus Infections - epidemiology ; COVID-19 ; Echocardiography ; Electrocardiography ; Female ; Glucocorticoids - therapeutic use ; Humans ; Male ; Middle Aged ; Myocarditis ; Myocarditis - diagnosis ; Myocarditis - drug therapy ; Myocarditis - etiology ; Pandemics ; Pneumonia, Viral - complications ; Pneumonia, Viral - epidemiology ; SARS-CoV-2 ; Severe acute respiratory syndrome coronavirus 2 ; ST Elevation Myocardial Infarction - diagnosis ; ST Elevation Myocardial Infarction - drug therapy ; ST Elevation Myocardial Infarction - etiology ; Thrombolytic Therapy - methods</subject><ispartof>Cardiovascular revascularization medicine, 2020-08, Vol.21 (8), p.946-949</ispartof><rights>2020 Elsevier Inc.</rights><rights>2020 Elsevier Inc. All rights reserved.</rights><rights>2020 Elsevier Inc. All rights reserved. 2020 Elsevier Inc.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c496t-c268cbc518d562c2dc99898dfd8f6dcc6484c44b3618811634373560ffca30fb3</citedby><cites>FETCH-LOGICAL-c496t-c268cbc518d562c2dc99898dfd8f6dcc6484c44b3618811634373560ffca30fb3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.carrev.2020.05.009$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>230,315,781,785,886,3551,27929,27930,46000</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32423791$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Khalid, Nauman</creatorcontrib><creatorcontrib>Chen, Yuefeng</creatorcontrib><creatorcontrib>Case, Brian C.</creatorcontrib><creatorcontrib>Shlofmitz, Evan</creatorcontrib><creatorcontrib>Wermers, Jason P.</creatorcontrib><creatorcontrib>Rogers, Toby</creatorcontrib><creatorcontrib>Ben-Dor, Itsik</creatorcontrib><creatorcontrib>Waksman, Ron</creatorcontrib><title>COVID-19 (SARS-CoV-2) and the Heart – An Ominous Association</title><title>Cardiovascular revascularization medicine</title><addtitle>Cardiovasc Revasc Med</addtitle><description>Coronavirus disease 2019 (COVID-19) is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Cardiovascular manifestations of COVID-19 are diverse and complex and include acute coronary syndrome, myocarditis masquerading as ST-segment elevation myocardial infarction, pericarditis and pericardial effusion. We present 2 cases of COVID-19 infection with myocardial involvement with distinct mechanistic pathways and outcomes. Important decision strategies such as the timing of cardiac catheterization (when indicated) and requirement of early hemodynamic support in critically ill patients are discussed.
•Cardiovascular manifestations of COVID-19 are diverse and complex.•We present 2 cases of COVID-19 infection with myocardial involvement.•We discuss strategies such as timing of cardiac catheterization (when indicated).</description><subject>Acute coronary syndrome</subject><subject>Adult</subject><subject>Betacoronavirus</subject><subject>Clinical</subject><subject>Complications</subject><subject>Coronary Angiography</subject><subject>Coronavirus Infections - complications</subject><subject>Coronavirus Infections - epidemiology</subject><subject>COVID-19</subject><subject>Echocardiography</subject><subject>Electrocardiography</subject><subject>Female</subject><subject>Glucocorticoids - therapeutic use</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Myocarditis</subject><subject>Myocarditis - diagnosis</subject><subject>Myocarditis - drug therapy</subject><subject>Myocarditis - etiology</subject><subject>Pandemics</subject><subject>Pneumonia, Viral - complications</subject><subject>Pneumonia, Viral - epidemiology</subject><subject>SARS-CoV-2</subject><subject>Severe acute respiratory syndrome coronavirus 2</subject><subject>ST Elevation Myocardial Infarction - diagnosis</subject><subject>ST Elevation Myocardial Infarction - drug therapy</subject><subject>ST Elevation Myocardial Infarction - etiology</subject><subject>Thrombolytic Therapy - methods</subject><issn>1553-8389</issn><issn>1878-0938</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kM1KAzEUhYMotlbfQGSWupgxPzOZZFMo9acFoWC125DeZGxKO1OSacGd7-Ab-iROqVbduLoXLuecez6EzglOCCb8ep6A9t5uEoopTnCWYCwPUJuIXMRYMnHY7FnGYsGEbKGTEOYYs5zy_Bi1GE0pyyVpo25_NBnexERGl-Pe4zjuV5OYXkW6NFE9s9HAal9HH2_vUa-MRktXVusQ9UKowOnaVeUpOir0Itizr9lBz3e3T_1B_DC6H_Z7DzGkktcxUC5gChkRJuMUqAEphRSmMKLgBoCnIoU0nTJOhCCEs5TlLOO4KEAzXExZB3V3vqv1dGkN2LL2eqFW3i21f1WVdurvpXQz9VJtVE5pzrFoDNKdAfgqBG-LvZZgteWp5mrHU215Kpyphmcju_iduxd9A_x5zDbtN856FcDZEqxx3kKtTOX-T_gEwn6HZQ</recordid><startdate>20200801</startdate><enddate>20200801</enddate><creator>Khalid, Nauman</creator><creator>Chen, Yuefeng</creator><creator>Case, Brian C.</creator><creator>Shlofmitz, Evan</creator><creator>Wermers, Jason P.</creator><creator>Rogers, Toby</creator><creator>Ben-Dor, Itsik</creator><creator>Waksman, Ron</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>5PM</scope></search><sort><creationdate>20200801</creationdate><title>COVID-19 (SARS-CoV-2) and the Heart – An Ominous Association</title><author>Khalid, Nauman ; Chen, Yuefeng ; Case, Brian C. ; Shlofmitz, Evan ; Wermers, Jason P. ; Rogers, Toby ; Ben-Dor, Itsik ; Waksman, Ron</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c496t-c268cbc518d562c2dc99898dfd8f6dcc6484c44b3618811634373560ffca30fb3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Acute coronary syndrome</topic><topic>Adult</topic><topic>Betacoronavirus</topic><topic>Clinical</topic><topic>Complications</topic><topic>Coronary Angiography</topic><topic>Coronavirus Infections - complications</topic><topic>Coronavirus Infections - epidemiology</topic><topic>COVID-19</topic><topic>Echocardiography</topic><topic>Electrocardiography</topic><topic>Female</topic><topic>Glucocorticoids - therapeutic use</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Myocarditis</topic><topic>Myocarditis - diagnosis</topic><topic>Myocarditis - drug therapy</topic><topic>Myocarditis - etiology</topic><topic>Pandemics</topic><topic>Pneumonia, Viral - complications</topic><topic>Pneumonia, Viral - epidemiology</topic><topic>SARS-CoV-2</topic><topic>Severe acute respiratory syndrome coronavirus 2</topic><topic>ST Elevation Myocardial Infarction - diagnosis</topic><topic>ST Elevation Myocardial Infarction - drug therapy</topic><topic>ST Elevation Myocardial Infarction - etiology</topic><topic>Thrombolytic Therapy - methods</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Khalid, Nauman</creatorcontrib><creatorcontrib>Chen, Yuefeng</creatorcontrib><creatorcontrib>Case, Brian C.</creatorcontrib><creatorcontrib>Shlofmitz, Evan</creatorcontrib><creatorcontrib>Wermers, Jason P.</creatorcontrib><creatorcontrib>Rogers, Toby</creatorcontrib><creatorcontrib>Ben-Dor, Itsik</creatorcontrib><creatorcontrib>Waksman, Ron</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Cardiovascular revascularization medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Khalid, Nauman</au><au>Chen, Yuefeng</au><au>Case, Brian C.</au><au>Shlofmitz, Evan</au><au>Wermers, Jason P.</au><au>Rogers, Toby</au><au>Ben-Dor, Itsik</au><au>Waksman, Ron</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>COVID-19 (SARS-CoV-2) and the Heart – An Ominous Association</atitle><jtitle>Cardiovascular revascularization medicine</jtitle><addtitle>Cardiovasc Revasc Med</addtitle><date>2020-08-01</date><risdate>2020</risdate><volume>21</volume><issue>8</issue><spage>946</spage><epage>949</epage><pages>946-949</pages><issn>1553-8389</issn><eissn>1878-0938</eissn><abstract>Coronavirus disease 2019 (COVID-19) is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Cardiovascular manifestations of COVID-19 are diverse and complex and include acute coronary syndrome, myocarditis masquerading as ST-segment elevation myocardial infarction, pericarditis and pericardial effusion. We present 2 cases of COVID-19 infection with myocardial involvement with distinct mechanistic pathways and outcomes. Important decision strategies such as the timing of cardiac catheterization (when indicated) and requirement of early hemodynamic support in critically ill patients are discussed.
•Cardiovascular manifestations of COVID-19 are diverse and complex.•We present 2 cases of COVID-19 infection with myocardial involvement.•We discuss strategies such as timing of cardiac catheterization (when indicated).</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>32423791</pmid><doi>10.1016/j.carrev.2020.05.009</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Acute coronary syndrome Adult Betacoronavirus Clinical Complications Coronary Angiography Coronavirus Infections - complications Coronavirus Infections - epidemiology COVID-19 Echocardiography Electrocardiography Female Glucocorticoids - therapeutic use Humans Male Middle Aged Myocarditis Myocarditis - diagnosis Myocarditis - drug therapy Myocarditis - etiology Pandemics Pneumonia, Viral - complications Pneumonia, Viral - epidemiology SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 ST Elevation Myocardial Infarction - diagnosis ST Elevation Myocardial Infarction - drug therapy ST Elevation Myocardial Infarction - etiology Thrombolytic Therapy - methods |
title | COVID-19 (SARS-CoV-2) and the Heart – An Ominous Association |
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