Clinical Presentation of COVID19 in Dementia Patients
No studies analyzing the role of dementia as a risk factor for mortality in patients affected by COVID-19. We assessed the prevalence, clinical presentation and outcomes of dementia among subjects hospitalized for COVID19 infection. Retrospective study. COVID wards in Acute Hospital in Brescia provi...
Gespeichert in:
| Veröffentlicht in: | The Journal of nutrition, health & aging health & aging, 2020-01, Vol.24 (6), p.560-562 |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 562 |
|---|---|
| container_issue | 6 |
| container_start_page | 560 |
| container_title | The Journal of nutrition, health & aging |
| container_volume | 24 |
| creator | Bianchetti, A Rozzini, R Guerini, F Boffelli, S Ranieri, P Minelli, G Bianchetti, L Trabucchi, M |
| description | No studies analyzing the role of dementia as a risk factor for mortality in patients affected by COVID-19. We assessed the prevalence, clinical presentation and outcomes of dementia among subjects hospitalized for COVID19 infection.
Retrospective study.
COVID wards in Acute Hospital in Brescia province, Northern Italy.
We used data from 627 subjects admitted to Acute Medical wards with COVID 19 pneumonia.
Clinical records of each patients admitted to the hospital with a diagnosis of COVID19 infection were retrospectively analyzed. Diagnosis of dementia, modalities of onset of the COVID-19 infection, symptoms of presentation at the hospital and outcomes were recorded.
Dementia was diagnosed in 82 patients (13.1%). The mortality rate was 62.2% (51/82) among patients affected by dementia compared to 26.2% (143/545) in subjects without dementia (p |
| doi_str_mv | 10.1007/s12603-020-1389-1 |
| format | Article |
| fullrecord | <record><control><sourceid>pubmed</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7227170</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>32510106</sourcerecordid><originalsourceid>FETCH-LOGICAL-p163t-80e0fd7568820721e8ebb8f09e9f325a0022703c1b04790b94e962c38c4beb283</originalsourceid><addsrcrecordid>eNpVkNtKAzEQhoMotq4-gDeSF4jOJLs53AiyrVootBfq7ZJssxrZE5sq-PYGPKBX88PHfDP8hJwjXCKAuorIJQgGHBgKbRgekDkqCSxXWh-mzJVhSoGakZMYXwHywmh5TGaCFwgIck6Ksg19qG1Lt5OPvt_bfRh6OjS03DytFmho6OnCd4kES7eJphRPyVFj2-jPvmdGHm-XD-U9W2_uVuXNmo0oxZ5p8NDsVCG15qA4eu2d0w0Yb5r0ggXgXIGo0UGuDDiTeyN5LXSdO--4Fhm5_vKOb67zuzrdnmxbjVPo7PRRDTZU_0kfXqrn4b1SSYxJnZGLv4LfzZ8CxCcElVyC</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Clinical Presentation of COVID19 in Dementia Patients</title><source>MEDLINE</source><source>Springer Nature - Complete Springer Journals</source><source>Alma/SFX Local Collection</source><creator>Bianchetti, A ; Rozzini, R ; Guerini, F ; Boffelli, S ; Ranieri, P ; Minelli, G ; Bianchetti, L ; Trabucchi, M</creator><creatorcontrib>Bianchetti, A ; Rozzini, R ; Guerini, F ; Boffelli, S ; Ranieri, P ; Minelli, G ; Bianchetti, L ; Trabucchi, M</creatorcontrib><description>No studies analyzing the role of dementia as a risk factor for mortality in patients affected by COVID-19. We assessed the prevalence, clinical presentation and outcomes of dementia among subjects hospitalized for COVID19 infection.
Retrospective study.
COVID wards in Acute Hospital in Brescia province, Northern Italy.
We used data from 627 subjects admitted to Acute Medical wards with COVID 19 pneumonia.
Clinical records of each patients admitted to the hospital with a diagnosis of COVID19 infection were retrospectively analyzed. Diagnosis of dementia, modalities of onset of the COVID-19 infection, symptoms of presentation at the hospital and outcomes were recorded.
Dementia was diagnosed in 82 patients (13.1%). The mortality rate was 62.2% (51/82) among patients affected by dementia compared to 26.2% (143/545) in subjects without dementia (p<0.001, Chi-Squared test). In a logistic regression model age, and the diagnosis of dementia resulted independently associated with a higher mortality, and patients diagnosed with dementia presented an OR of 1.84 (95% CI: 1.09-3.13, p<0.05). Among patients diagnosed with dementia the most frequent symptoms of onset were delirium, especially in the hypoactive form, and worsening of the functional status.
The diagnosis of dementia, especially in the most advanced stages, represents an important risk factor for mortality in COVID-19 patients. The clinical presentation of COVID-19 in subjects with dementia is atypical, reducing early recognition of symptoms and hospitalization.</description><identifier>ISSN: 1279-7707</identifier><identifier>EISSN: 1760-4788</identifier><identifier>DOI: 10.1007/s12603-020-1389-1</identifier><identifier>PMID: 32510106</identifier><language>eng</language><publisher>France: Springer Paris</publisher><subject>Aged ; Aged, 80 and over ; Betacoronavirus ; Coronavirus Infections - complications ; COVID-19 ; Dementia - complications ; Dementia - epidemiology ; Female ; Humans ; Italy - epidemiology ; Logistic Models ; Male ; Middle Aged ; Pandemics ; Pneumonia, Viral - complications ; Prevalence ; Retrospective Studies ; Risk Factors ; SARS-CoV-2</subject><ispartof>The Journal of nutrition, health & aging, 2020-01, Vol.24 (6), p.560-562</ispartof><rights>Serdi and Springer-Verlag International SAS, part of Springer Nature 2020</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,777,781,882,27905,27906</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32510106$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bianchetti, A</creatorcontrib><creatorcontrib>Rozzini, R</creatorcontrib><creatorcontrib>Guerini, F</creatorcontrib><creatorcontrib>Boffelli, S</creatorcontrib><creatorcontrib>Ranieri, P</creatorcontrib><creatorcontrib>Minelli, G</creatorcontrib><creatorcontrib>Bianchetti, L</creatorcontrib><creatorcontrib>Trabucchi, M</creatorcontrib><title>Clinical Presentation of COVID19 in Dementia Patients</title><title>The Journal of nutrition, health & aging</title><addtitle>J Nutr Health Aging</addtitle><description>No studies analyzing the role of dementia as a risk factor for mortality in patients affected by COVID-19. We assessed the prevalence, clinical presentation and outcomes of dementia among subjects hospitalized for COVID19 infection.
Retrospective study.
COVID wards in Acute Hospital in Brescia province, Northern Italy.
We used data from 627 subjects admitted to Acute Medical wards with COVID 19 pneumonia.
Clinical records of each patients admitted to the hospital with a diagnosis of COVID19 infection were retrospectively analyzed. Diagnosis of dementia, modalities of onset of the COVID-19 infection, symptoms of presentation at the hospital and outcomes were recorded.
Dementia was diagnosed in 82 patients (13.1%). The mortality rate was 62.2% (51/82) among patients affected by dementia compared to 26.2% (143/545) in subjects without dementia (p<0.001, Chi-Squared test). In a logistic regression model age, and the diagnosis of dementia resulted independently associated with a higher mortality, and patients diagnosed with dementia presented an OR of 1.84 (95% CI: 1.09-3.13, p<0.05). Among patients diagnosed with dementia the most frequent symptoms of onset were delirium, especially in the hypoactive form, and worsening of the functional status.
The diagnosis of dementia, especially in the most advanced stages, represents an important risk factor for mortality in COVID-19 patients. The clinical presentation of COVID-19 in subjects with dementia is atypical, reducing early recognition of symptoms and hospitalization.</description><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Betacoronavirus</subject><subject>Coronavirus Infections - complications</subject><subject>COVID-19</subject><subject>Dementia - complications</subject><subject>Dementia - epidemiology</subject><subject>Female</subject><subject>Humans</subject><subject>Italy - epidemiology</subject><subject>Logistic Models</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Pandemics</subject><subject>Pneumonia, Viral - complications</subject><subject>Prevalence</subject><subject>Retrospective Studies</subject><subject>Risk Factors</subject><subject>SARS-CoV-2</subject><issn>1279-7707</issn><issn>1760-4788</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVkNtKAzEQhoMotq4-gDeSF4jOJLs53AiyrVootBfq7ZJssxrZE5sq-PYGPKBX88PHfDP8hJwjXCKAuorIJQgGHBgKbRgekDkqCSxXWh-mzJVhSoGakZMYXwHywmh5TGaCFwgIck6Ksg19qG1Lt5OPvt_bfRh6OjS03DytFmho6OnCd4kES7eJphRPyVFj2-jPvmdGHm-XD-U9W2_uVuXNmo0oxZ5p8NDsVCG15qA4eu2d0w0Yb5r0ggXgXIGo0UGuDDiTeyN5LXSdO--4Fhm5_vKOb67zuzrdnmxbjVPo7PRRDTZU_0kfXqrn4b1SSYxJnZGLv4LfzZ8CxCcElVyC</recordid><startdate>20200101</startdate><enddate>20200101</enddate><creator>Bianchetti, A</creator><creator>Rozzini, R</creator><creator>Guerini, F</creator><creator>Boffelli, S</creator><creator>Ranieri, P</creator><creator>Minelli, G</creator><creator>Bianchetti, L</creator><creator>Trabucchi, M</creator><general>Springer Paris</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>5PM</scope></search><sort><creationdate>20200101</creationdate><title>Clinical Presentation of COVID19 in Dementia Patients</title><author>Bianchetti, A ; Rozzini, R ; Guerini, F ; Boffelli, S ; Ranieri, P ; Minelli, G ; Bianchetti, L ; Trabucchi, M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p163t-80e0fd7568820721e8ebb8f09e9f325a0022703c1b04790b94e962c38c4beb283</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Betacoronavirus</topic><topic>Coronavirus Infections - complications</topic><topic>COVID-19</topic><topic>Dementia - complications</topic><topic>Dementia - epidemiology</topic><topic>Female</topic><topic>Humans</topic><topic>Italy - epidemiology</topic><topic>Logistic Models</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Pandemics</topic><topic>Pneumonia, Viral - complications</topic><topic>Prevalence</topic><topic>Retrospective Studies</topic><topic>Risk Factors</topic><topic>SARS-CoV-2</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bianchetti, A</creatorcontrib><creatorcontrib>Rozzini, R</creatorcontrib><creatorcontrib>Guerini, F</creatorcontrib><creatorcontrib>Boffelli, S</creatorcontrib><creatorcontrib>Ranieri, P</creatorcontrib><creatorcontrib>Minelli, G</creatorcontrib><creatorcontrib>Bianchetti, L</creatorcontrib><creatorcontrib>Trabucchi, M</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>The Journal of nutrition, health & aging</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bianchetti, A</au><au>Rozzini, R</au><au>Guerini, F</au><au>Boffelli, S</au><au>Ranieri, P</au><au>Minelli, G</au><au>Bianchetti, L</au><au>Trabucchi, M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Clinical Presentation of COVID19 in Dementia Patients</atitle><jtitle>The Journal of nutrition, health & aging</jtitle><addtitle>J Nutr Health Aging</addtitle><date>2020-01-01</date><risdate>2020</risdate><volume>24</volume><issue>6</issue><spage>560</spage><epage>562</epage><pages>560-562</pages><issn>1279-7707</issn><eissn>1760-4788</eissn><abstract>No studies analyzing the role of dementia as a risk factor for mortality in patients affected by COVID-19. We assessed the prevalence, clinical presentation and outcomes of dementia among subjects hospitalized for COVID19 infection.
Retrospective study.
COVID wards in Acute Hospital in Brescia province, Northern Italy.
We used data from 627 subjects admitted to Acute Medical wards with COVID 19 pneumonia.
Clinical records of each patients admitted to the hospital with a diagnosis of COVID19 infection were retrospectively analyzed. Diagnosis of dementia, modalities of onset of the COVID-19 infection, symptoms of presentation at the hospital and outcomes were recorded.
Dementia was diagnosed in 82 patients (13.1%). The mortality rate was 62.2% (51/82) among patients affected by dementia compared to 26.2% (143/545) in subjects without dementia (p<0.001, Chi-Squared test). In a logistic regression model age, and the diagnosis of dementia resulted independently associated with a higher mortality, and patients diagnosed with dementia presented an OR of 1.84 (95% CI: 1.09-3.13, p<0.05). Among patients diagnosed with dementia the most frequent symptoms of onset were delirium, especially in the hypoactive form, and worsening of the functional status.
The diagnosis of dementia, especially in the most advanced stages, represents an important risk factor for mortality in COVID-19 patients. The clinical presentation of COVID-19 in subjects with dementia is atypical, reducing early recognition of symptoms and hospitalization.</abstract><cop>France</cop><pub>Springer Paris</pub><pmid>32510106</pmid><doi>10.1007/s12603-020-1389-1</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1279-7707 |
| ispartof | The Journal of nutrition, health & aging, 2020-01, Vol.24 (6), p.560-562 |
| issn | 1279-7707 1760-4788 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7227170 |
| source | MEDLINE; Springer Nature - Complete Springer Journals; Alma/SFX Local Collection |
| subjects | Aged Aged, 80 and over Betacoronavirus Coronavirus Infections - complications COVID-19 Dementia - complications Dementia - epidemiology Female Humans Italy - epidemiology Logistic Models Male Middle Aged Pandemics Pneumonia, Viral - complications Prevalence Retrospective Studies Risk Factors SARS-CoV-2 |
| title | Clinical Presentation of COVID19 in Dementia Patients |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-20T09%3A09%3A16IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-pubmed&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Clinical%20Presentation%20of%20COVID19%20in%20Dementia%20Patients&rft.jtitle=The%20Journal%20of%20nutrition,%20health%20&%20aging&rft.au=Bianchetti,%20A&rft.date=2020-01-01&rft.volume=24&rft.issue=6&rft.spage=560&rft.epage=562&rft.pages=560-562&rft.issn=1279-7707&rft.eissn=1760-4788&rft_id=info:doi/10.1007/s12603-020-1389-1&rft_dat=%3Cpubmed%3E32510106%3C/pubmed%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/32510106&rfr_iscdi=true |