Therapeutic Strategies and Biomarkers to Modulate PARP Activity for Targeted Cancer Therapy

Poly-(ADP-ribose) polymerase 1 (PARP1) is commonly known for its vital role in DNA damage response and repair. However, its enzymatic activity has been linked to a plethora of physiological and pathophysiological transactions ranging from cellular proliferation, survival and death. For instance, mal...

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Veröffentlicht in:	Cancers 2020-04, Vol.12 (4), p.972
Hauptverfasser:	Singh, Naveen, Pay, S Louise, Bhandare, Snehal B, Arimpur, Udhaya, Motea, Edward A
Format:	Artikel
Sprache:	eng
Schlagworte:	Review
Online-Zugang:	Volltext
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