Utility of isocitrate dehydrogenase 1 as a serum protein biomarker for the early detection of non‐small‐cell lung cancer: A multicenter in vitro diagnostic clinical trial

We aimed to verify the expression status and diagnostic significance of isocitrate dehydrogenase 1 (IDH1) in non‐small‐cell lung cancer (NSCLC), especially during early stages. Serum IDH1 levels were measured by ELISA. A total of 1223 participants (660 patients with NSCLC, 276 healthy controls [HCs]...

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Veröffentlicht in:	Cancer science 2020-05, Vol.111 (5), p.1739-1749
Hauptverfasser:	Sun, Nan, Sun, Shouguo, Gao, Yibo, Li, Yuan, Lu, Zhiliang, Yuan, Zuyang, Che, Yun, Huang, Jianbing, Mao, Shuangshuang, Lei, Yuanyuan, Zang, Ruochuan, Li, Ning, Cui, Wei, Qi, Jun, Chen, Feng, Gao, Jia, Wang, Jinling, Min, Rong, Chen, Yan, Shi, Guangli, Tan, Fengwei, He, Jie
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers blood biomarker Cancer therapies Clinical trials Dehydrogenases diagnosis Disease early detection Enzymes Hospitals IDH1 Isocitrate dehydrogenase Lung cancer Medical prognosis Medical screening MicroRNAs Mortality Mutation Non-small cell lung carcinoma NSCLC Original Tomography Tumors
Online-Zugang:	Volltext
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