Long noncoding RNA metastasis‐associated lung adenocarcinoma transcript 1 cooperates with enhancer of zeste homolog 2 to promote hepatocellular carcinoma development by modulating the microRNA‐22/Snail family transcriptional repressor 1 axis

Metastasis‐associated lung adenocarcinoma transcript 1 (MALAT1) is an oncogenic long noncoding RNA that has been found to promote carcinogenesis and metastasis in many tumors. However, the underlying role of MALAT1 in the progression and metastasis of hepatocellular carcinoma (HCC) remains unclear....

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Veröffentlicht in:	Cancer science 2020-05, Vol.111 (5), p.1582-1595
Hauptverfasser:	Chen, Shaofei, Wang, Guobin, Tao, Kaixiong, Cai, Kailin, Wu, Ke, Ye, Lin, Bai, Jie, Yin, Yuping, Wang, Jiliang, Shuai, Xiaoming, Gao, Jinbo, Pu, Jiarui, Li, Hang
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma Binding sites Carcinogenesis Cell adhesion & migration Cell growth Deoxyribonucleic acid DNA EZH2 Gene expression Genomes Hepatocellular carcinoma Liver cancer MALAT1 Mesenchyme Metastases Metastasis MicroRNAs miRNA miR‐22 Original Proteins SNAI1 Snail protein Transcription Tumors
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