Prostaglandin F2α agonist-induced suppression of 3T3-L1 cell adipogenesis affects spatial formation of extra-cellular matrix

To establish a deepening of the upper eyelid sulcus (DUES) model that can be induced by prostaglandin (PG) analogues, a three-dimension (3D) tissue culture was employed. Upon adipogenesis of the 3T3-L1 organoid, the effects of either Bimatoprost acid (BIM-A), or PGF2α were examined. During the adipo...

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Veröffentlicht in:	Scientific reports 2020-05, Vol.10 (1), p.7958-7958, Article 7958
Hauptverfasser:	Ida, Yosuke, Hikage, Fumihito, Itoh, Kaku, Ida, Haruka, Ohguro, Hiroshi
Format:	Artikel
Sprache:	eng
Schlagworte:	13/1 13/106 3T3-L1 Cells 631/154/309/436/108 692/699/3161/3169/3170 Adipocytes Adipogenesis Adipogenesis - drug effects Animals Cell culture Dinoprost - agonists Etiology Extracellular matrix Extracellular Matrix - drug effects Extracellular Matrix - metabolism Eyelid Fatty acids Gene expression Growth factors Humanities and Social Sciences Immunocytochemistry Lipids Mice multidisciplinary Organoids Science Science (multidisciplinary) Time Factors Tissue culture
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