Identification of Human Single-Domain Antibodies against SARS-CoV-2

The worldwide spread of COVID-19 highlights the need for an efficient approach to rapidly develop therapeutics and prophylactics against SARS-CoV-2. The SARS-CoV-2 spike protein, containing the receptor-binding domain (RBD) and S1 subunit involved in receptor engagement, is a potential therapeutic t...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cell host & microbe 2020-06, Vol.27 (6), p.891-898.e5
Hauptverfasser:	Wu, Yanling, Li, Cheng, Xia, Shuai, Tian, Xiaolong, Kong, Yu, Wang, Zhi, Gu, Chenjian, Zhang, Rong, Tu, Chao, Xie, Youhua, Yang, Zhenlin, Lu, Lu, Jiang, Shibo, Ying, Tianlei
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies, Monoclonal - chemistry Antibodies, Monoclonal - immunology Antibodies, Neutralizing - immunology CR3022 Epitopes - immunology Humans Immunoglobulin Heavy Chains Immunoglobulin Variable Region Models, Molecular nanobody Peptide Library Protein Domains RBD SARS-CoV-2 Single-Domain Antibodies - chemistry Single-Domain Antibodies - immunology Single-Domain Antibodies - isolation & purification single-domain antibody Spike Glycoprotein, Coronavirus - chemistry trimeric interface
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!