Mesenchymal Stem Cells for Coronavirus (COVID-19)-Induced Pneumonia: Revisiting the Paracrine Hypothesis with New Hopes?
Mesenchymal stem cells (MSCs) bear a promising potential for regenerative medicine therapies and they repair damaged tissue through secretion of immune modulatory and anti-inflammatory molecules acting in a paracrine fashion. Coronavirus disease 2019 (COVID-19) has spread all over the world with hig...
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| Veröffentlicht in: | Aging and disease 2020-06, Vol.11 (3), p.477-479 |
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| container_title | Aging and disease |
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| creator | Ozturk, Selcuk Elcin, Ayse Eser Elcin, Yasar Murat |
| description | Mesenchymal stem cells (MSCs) bear a promising potential for regenerative medicine therapies and they repair damaged tissue through secretion of immune modulatory and anti-inflammatory molecules acting in a paracrine fashion. Coronavirus disease 2019 (COVID-19) has spread all over the world with high morbidity and mortality rates and there is no specific treatment for this infection. A recent study published in the journal reports that MSC infusion is safe and effective in patients suffering from COVID-19 induced pneumonia. In the light of this study and previous reports, we make additional comments about possible therapeutic effects of MSCs in COVID-19 infection. |
| doi_str_mv | 10.14336/AD.2020.0403 |
| format | Article |
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Coronavirus disease 2019 (COVID-19) has spread all over the world with high morbidity and mortality rates and there is no specific treatment for this infection. A recent study published in the journal reports that MSC infusion is safe and effective in patients suffering from COVID-19 induced pneumonia. 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In the light of this study and previous reports, we make additional comments about possible therapeutic effects of MSCs in COVID-19 infection.</description><subject>Care and treatment</subject><subject>Coronaviruses</subject><subject>COVID-19</subject><subject>Health aspects</subject><subject>Medical research</subject><subject>Pneumonia</subject><subject>Stem cell transplantation</subject><subject>Stem cells</subject><issn>2152-5250</issn><issn>2152-5250</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><recordid>eNptks9v2yAUx61p1Vq1Pe46Ie3SHZxhwNjssCpy1iVSu1b7dUUYPydMNmRgp8t_X9K0VSsNDjw9Pu8LfHlJ8jbDk4xRyj9OZxOCCZ5ghumr5IhkOUlzkuPXz-LD5DSEPzgOKggV9E1ySAkrBRfsKPl3BQGsXm171aEfA_Sogq4LqHUeVc47qzbGjwGdVde_F7M0Ex_ShW1GDQ26sTD2zhr1CX2HjQlmMHaJhhWgG-WV9sYCmm_XLmaCCejWDCv0DW7R3K0hnJ8kB63qApw-rMfJr4svP6t5enn9dVFNL1PNcjakGdaiLEtVYGhr3Sie06LmTc7rBggRRVNwTgVmdamBNYzTXGBdcqFKgjXnGT1OPu9112PdQ6PBDl51cu1Nr_xWOmXkyx1rVnLpNrIg0VmBo8DZg4B3f0cIg-xN0NEkZcGNQRKGRRbdvD_r_R5dqg6ksa2LinqHyyknRZ5xJopITf5DxdlAb7Sz0JqYf1GQ7gu0dyF4aJ9un2F53wdyOpO7PpC7Poj8u-dPfqIff53eAcaOq_8</recordid><startdate>20200601</startdate><enddate>20200601</enddate><creator>Ozturk, Selcuk</creator><creator>Elcin, Ayse Eser</creator><creator>Elcin, Yasar Murat</creator><general>JKL International</general><general>JKL International LLC</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20200601</creationdate><title>Mesenchymal Stem Cells for Coronavirus (COVID-19)-Induced Pneumonia: Revisiting the Paracrine Hypothesis with New Hopes?</title><author>Ozturk, Selcuk ; Elcin, Ayse Eser ; Elcin, Yasar Murat</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c454t-10c9888a70efbcda6537b6d56bde2297d7663904b8ce4d463590c869a820c6613</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Care and treatment</topic><topic>Coronaviruses</topic><topic>COVID-19</topic><topic>Health aspects</topic><topic>Medical research</topic><topic>Pneumonia</topic><topic>Stem cell transplantation</topic><topic>Stem cells</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ozturk, Selcuk</creatorcontrib><creatorcontrib>Elcin, Ayse Eser</creatorcontrib><creatorcontrib>Elcin, Yasar Murat</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Aging and disease</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ozturk, Selcuk</au><au>Elcin, Ayse Eser</au><au>Elcin, Yasar Murat</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Mesenchymal Stem Cells for Coronavirus (COVID-19)-Induced Pneumonia: Revisiting the Paracrine Hypothesis with New Hopes?</atitle><jtitle>Aging and disease</jtitle><addtitle>Aging Dis</addtitle><date>2020-06-01</date><risdate>2020</risdate><volume>11</volume><issue>3</issue><spage>477</spage><epage>479</epage><pages>477-479</pages><issn>2152-5250</issn><eissn>2152-5250</eissn><abstract>Mesenchymal stem cells (MSCs) bear a promising potential for regenerative medicine therapies and they repair damaged tissue through secretion of immune modulatory and anti-inflammatory molecules acting in a paracrine fashion. 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| ispartof | Aging and disease, 2020-06, Vol.11 (3), p.477-479 |
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| source | DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central |
| subjects | Care and treatment Coronaviruses COVID-19 Health aspects Medical research Pneumonia Stem cell transplantation Stem cells |
| title | Mesenchymal Stem Cells for Coronavirus (COVID-19)-Induced Pneumonia: Revisiting the Paracrine Hypothesis with New Hopes? |
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