Neuroanatomical correlates of phonologic errors in logopenic progressive aphasia

•This study examined neuroimaging correlates of phonologic errors in lvPPA.•The inferior parietal lobe and supramarginal gyrus had the strongest correlates.•Atrophy was associated with a greater likelihood of substitution errors in lvPPA.•Thus, specific parietal region atrophy may increase phonologic errors in lvPPA.•The results support prior findings of temporoparietal cortex atrophy in lvPPA. While phonologic errors may be one of the salient features of the logopenic variant of primary progressive aphasia (lvPPA), sparse data are available on their neuroimaging correlates. The purpose of this study was to identify brain regions associated with different types of phonologic errors across several tasks for participants with lvPPA. Correlational analyses between phonologic errors across tasks most likely to elicit such errors and specific left hemisphere gray matter volume regions were conducted for 20 participants. Findings point to the inferior parietal lobe and supramarginal gyrus as being the most relevant correlates. Atrophy in these regions may increase the likelihood of making phonologic errors in lvPPA, particularly substitution error types. Our results provide support for neuroanatomical correlates of phonologic errors in the parietal region, which is consistent with previous findings of temporoparietal cortex involvement/atrophy in lvPPA.