A model based study on the dynamics of COVID-19: Prediction and control
•A mathematical model has been proposed to analyse the pandemic COVID-19.•The model has been analysed both theoretically and numerically.•The procedure to control the basic reproduction number R0 has been provided.•We have formed an optimal control problem where governmental policy is the control.•T...
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Veröffentlicht in: | Chaos, solitons and fractals solitons and fractals, 2020-07, Vol.136, p.109889-109889, Article 109889 |
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creator | Mandal, Manotosh Jana, Soovoojeet Nandi, Swapan Kumar Khatua, Anupam Adak, Sayani Kar, T.K. |
description | •A mathematical model has been proposed to analyse the pandemic COVID-19.•The model has been analysed both theoretically and numerically.•The procedure to control the basic reproduction number R0 has been provided.•We have formed an optimal control problem where governmental policy is the control.•The model is used for short term prediction of COVID-19 in three states of India.
As there is no vaccination and proper medicine for treatment, the recent pandemic caused by COVID-19 has drawn attention to the strategies of quarantine and other governmental measures, like lockdown, media coverage on social isolation, and improvement of public hygiene, etc to control the disease. The mathematical model can help when these intervention measures are the best strategies for disease control as well as how they might affect the disease dynamics. Motivated by this, in this article, we have formulated a mathematical model introducing a quarantine class and governmental intervention measures to mitigate disease transmission. We study a thorough dynamical behavior of the model in terms of the basic reproduction number. Further, we perform the sensitivity analysis of the essential reproduction number and found that reducing the contact of exposed and susceptible humans is the most critical factor in achieving disease control. To lessen the infected individuals as well as to minimize the cost of implementing government control measures, we formulate an optimal control problem, and optimal control is determined. Finally, we forecast a short-term trend of COVID-19 for the three highly affected states, Maharashtra, Delhi, and Tamil Nadu, in India, and it suggests that the first two states need further monitoring of control measures to reduce the contact of exposed and susceptible humans. |
doi_str_mv | 10.1016/j.chaos.2020.109889 |
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As there is no vaccination and proper medicine for treatment, the recent pandemic caused by COVID-19 has drawn attention to the strategies of quarantine and other governmental measures, like lockdown, media coverage on social isolation, and improvement of public hygiene, etc to control the disease. The mathematical model can help when these intervention measures are the best strategies for disease control as well as how they might affect the disease dynamics. Motivated by this, in this article, we have formulated a mathematical model introducing a quarantine class and governmental intervention measures to mitigate disease transmission. We study a thorough dynamical behavior of the model in terms of the basic reproduction number. Further, we perform the sensitivity analysis of the essential reproduction number and found that reducing the contact of exposed and susceptible humans is the most critical factor in achieving disease control. To lessen the infected individuals as well as to minimize the cost of implementing government control measures, we formulate an optimal control problem, and optimal control is determined. Finally, we forecast a short-term trend of COVID-19 for the three highly affected states, Maharashtra, Delhi, and Tamil Nadu, in India, and it suggests that the first two states need further monitoring of control measures to reduce the contact of exposed and susceptible humans.</description><identifier>ISSN: 0960-0779</identifier><identifier>EISSN: 1873-2887</identifier><identifier>EISSN: 0960-0779</identifier><identifier>DOI: 10.1016/j.chaos.2020.109889</identifier><identifier>PMID: 32406395</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Bang-bang and singular control ; Basic reproduction number ; Short term prediction of COVID-19 ; Theoretical epidemiology ; Transcritical bifurcation</subject><ispartof>Chaos, solitons and fractals, 2020-07, Vol.136, p.109889-109889, Article 109889</ispartof><rights>2020 Elsevier Ltd</rights><rights>2020 Elsevier Ltd. All rights reserved.</rights><rights>2020 Elsevier Ltd. All rights reserved. 2020 Elsevier Ltd</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c525t-1ad31d801c2dbc852d5f2c912e2bb2ee106bbc99ae3c1bb4d6f1b327764825ba3</citedby><cites>FETCH-LOGICAL-c525t-1ad31d801c2dbc852d5f2c912e2bb2ee106bbc99ae3c1bb4d6f1b327764825ba3</cites><orcidid>0000-0002-0123-9940 ; 0000-0001-7723-1489 ; 0000-0001-7349-6084</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.chaos.2020.109889$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>230,314,780,784,885,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32406395$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mandal, Manotosh</creatorcontrib><creatorcontrib>Jana, Soovoojeet</creatorcontrib><creatorcontrib>Nandi, Swapan Kumar</creatorcontrib><creatorcontrib>Khatua, Anupam</creatorcontrib><creatorcontrib>Adak, Sayani</creatorcontrib><creatorcontrib>Kar, T.K.</creatorcontrib><title>A model based study on the dynamics of COVID-19: Prediction and control</title><title>Chaos, solitons and fractals</title><addtitle>Chaos Solitons Fractals</addtitle><description>•A mathematical model has been proposed to analyse the pandemic COVID-19.•The model has been analysed both theoretically and numerically.•The procedure to control the basic reproduction number R0 has been provided.•We have formed an optimal control problem where governmental policy is the control.•The model is used for short term prediction of COVID-19 in three states of India.
As there is no vaccination and proper medicine for treatment, the recent pandemic caused by COVID-19 has drawn attention to the strategies of quarantine and other governmental measures, like lockdown, media coverage on social isolation, and improvement of public hygiene, etc to control the disease. The mathematical model can help when these intervention measures are the best strategies for disease control as well as how they might affect the disease dynamics. Motivated by this, in this article, we have formulated a mathematical model introducing a quarantine class and governmental intervention measures to mitigate disease transmission. We study a thorough dynamical behavior of the model in terms of the basic reproduction number. Further, we perform the sensitivity analysis of the essential reproduction number and found that reducing the contact of exposed and susceptible humans is the most critical factor in achieving disease control. To lessen the infected individuals as well as to minimize the cost of implementing government control measures, we formulate an optimal control problem, and optimal control is determined. Finally, we forecast a short-term trend of COVID-19 for the three highly affected states, Maharashtra, Delhi, and Tamil Nadu, in India, and it suggests that the first two states need further monitoring of control measures to reduce the contact of exposed and susceptible humans.</description><subject>Bang-bang and singular control</subject><subject>Basic reproduction number</subject><subject>Short term prediction of COVID-19</subject><subject>Theoretical epidemiology</subject><subject>Transcritical bifurcation</subject><issn>0960-0779</issn><issn>1873-2887</issn><issn>0960-0779</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><recordid>eNp9kVtLKzEUhYMoWi-_QJA8-jI9uXRmEkGh1CsI-qC-hlz22JSZiSZTof_-pNYj-nKeAjvfXmuzFkLHlIwpodWfxdjOdUhjRth6IoWQW2hERc0LJkS9jUZEVqQgdS330H5KC0IIJRXbRXucTUjFZTlCN1PcBQctNjqBw2lYuhUOPR7mgN2q1523CYcGzx5e7i4LKs_wYwTn7eAzpHuHbeiHGNpDtNPoNsHR13uAnq-vnma3xf3Dzd1sel_YkpVDQbXj1AlCLXPGipK5smFWUgbMGAaQ7zPGSqmBW2rMxFUNNZzVdTURrDSaH6CLje7b0nTgLGR33aq36DsdVypor37_9H6uXsOHqhkVXE6ywOmXQAzvS0iD6nyy0La6h7BMKifDCa9LyjLKN6iNIaUIzbcNJWpdgVqozwrUugK1qSBvnfy88HvnX-YZON8AkHP68BBVsh56m2ONYAflgv-vwV8C_Zhe</recordid><startdate>20200701</startdate><enddate>20200701</enddate><creator>Mandal, Manotosh</creator><creator>Jana, Soovoojeet</creator><creator>Nandi, Swapan Kumar</creator><creator>Khatua, Anupam</creator><creator>Adak, Sayani</creator><creator>Kar, T.K.</creator><general>Elsevier Ltd</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-0123-9940</orcidid><orcidid>https://orcid.org/0000-0001-7723-1489</orcidid><orcidid>https://orcid.org/0000-0001-7349-6084</orcidid></search><sort><creationdate>20200701</creationdate><title>A model based study on the dynamics of COVID-19: Prediction and control</title><author>Mandal, Manotosh ; Jana, Soovoojeet ; Nandi, Swapan Kumar ; Khatua, Anupam ; Adak, Sayani ; Kar, T.K.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c525t-1ad31d801c2dbc852d5f2c912e2bb2ee106bbc99ae3c1bb4d6f1b327764825ba3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Bang-bang and singular control</topic><topic>Basic reproduction number</topic><topic>Short term prediction of COVID-19</topic><topic>Theoretical epidemiology</topic><topic>Transcritical bifurcation</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mandal, Manotosh</creatorcontrib><creatorcontrib>Jana, Soovoojeet</creatorcontrib><creatorcontrib>Nandi, Swapan Kumar</creatorcontrib><creatorcontrib>Khatua, Anupam</creatorcontrib><creatorcontrib>Adak, Sayani</creatorcontrib><creatorcontrib>Kar, T.K.</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Chaos, solitons and fractals</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mandal, Manotosh</au><au>Jana, Soovoojeet</au><au>Nandi, Swapan Kumar</au><au>Khatua, Anupam</au><au>Adak, Sayani</au><au>Kar, T.K.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A model based study on the dynamics of COVID-19: Prediction and control</atitle><jtitle>Chaos, solitons and fractals</jtitle><addtitle>Chaos Solitons Fractals</addtitle><date>2020-07-01</date><risdate>2020</risdate><volume>136</volume><spage>109889</spage><epage>109889</epage><pages>109889-109889</pages><artnum>109889</artnum><issn>0960-0779</issn><eissn>1873-2887</eissn><eissn>0960-0779</eissn><abstract>•A mathematical model has been proposed to analyse the pandemic COVID-19.•The model has been analysed both theoretically and numerically.•The procedure to control the basic reproduction number R0 has been provided.•We have formed an optimal control problem where governmental policy is the control.•The model is used for short term prediction of COVID-19 in three states of India.
As there is no vaccination and proper medicine for treatment, the recent pandemic caused by COVID-19 has drawn attention to the strategies of quarantine and other governmental measures, like lockdown, media coverage on social isolation, and improvement of public hygiene, etc to control the disease. The mathematical model can help when these intervention measures are the best strategies for disease control as well as how they might affect the disease dynamics. Motivated by this, in this article, we have formulated a mathematical model introducing a quarantine class and governmental intervention measures to mitigate disease transmission. We study a thorough dynamical behavior of the model in terms of the basic reproduction number. Further, we perform the sensitivity analysis of the essential reproduction number and found that reducing the contact of exposed and susceptible humans is the most critical factor in achieving disease control. To lessen the infected individuals as well as to minimize the cost of implementing government control measures, we formulate an optimal control problem, and optimal control is determined. Finally, we forecast a short-term trend of COVID-19 for the three highly affected states, Maharashtra, Delhi, and Tamil Nadu, in India, and it suggests that the first two states need further monitoring of control measures to reduce the contact of exposed and susceptible humans.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>32406395</pmid><doi>10.1016/j.chaos.2020.109889</doi><tpages>1</tpages><orcidid>https://orcid.org/0000-0002-0123-9940</orcidid><orcidid>https://orcid.org/0000-0001-7723-1489</orcidid><orcidid>https://orcid.org/0000-0001-7349-6084</orcidid><oa>free_for_read</oa></addata></record> |
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subjects | Bang-bang and singular control Basic reproduction number Short term prediction of COVID-19 Theoretical epidemiology Transcritical bifurcation |
title | A model based study on the dynamics of COVID-19: Prediction and control |
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