Immune phenotype and histopathological growth pattern in patients with colorectal liver metastases

Background Patients with desmoplastic (angiogenic) histopathological growth pattern (HGP) colorectal liver metastases (CLM) might derive more benefit from bevacizumab-based chemotherapy than those with replacement (non-angiogenic) HGP. This study investigated the association of HGP with the immune p...

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Veröffentlicht in:	British journal of cancer 2020-05, Vol.122 (10), p.1518-1524
Hauptverfasser:	Stremitzer, Stefan, Vermeulen, Peter, Graver, Shannon, Kockx, Mark, Dirix, Luc, Yang, Dongyun, Zhang, Wu, Stift, Judith, Wrba, Friedrich, Gruenberger, Thomas, Lenz, Heinz-Josef, Scherer, Stefan J.
Format:	Artikel
Sprache:	eng
Schlagworte:	692/4028/546 692/4028/67/1504/1885/1393 692/4028/67/1504/1885/1777 692/53/2422 692/53/2423 Adult Aged Aged, 80 and over Angiogenesis Bevacizumab Bevacizumab - administration & dosage Biomedical and Life Sciences Biomedicine Cancer Research Cell Proliferation - drug effects Chemotherapy Colorectal Neoplasms - drug therapy Colorectal Neoplasms - genetics Colorectal Neoplasms - pathology Colorectal Neoplasms - surgery Combined Modality Therapy Disease-Free Survival Drug Resistance Epidemiology Female Growth patterns Hepatectomy - methods Humans Inflammation Liver Liver Neoplasms - drug therapy Liver Neoplasms - genetics Liver Neoplasms - pathology Liver Neoplasms - secondary Male Metastases Metastasis Middle Aged Molecular Medicine Monoclonal antibodies Neoadjuvant Therapy - methods Neoplasm Metastasis Neoplasm Recurrence, Local - drug therapy Neoplasm Recurrence, Local - genetics Neoplasm Recurrence, Local - pathology Oncology Patients Phenotype Phenotypes Survival Targeted cancer therapy
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