Primary renal lymphoma: A population‐based analysis using the SEER program (1973‐2015)
Objective Primary renal lymphoma (PRL) is defined as a non‐Hodgkin lymphoma (NHL) restricted to kidneys without extensive nodal disease. The literature on epidemiology and outcome in PRL is limited to case reports and small case series. Methods We utilized Surveillance, Epidemiology, and End Result...
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| Veröffentlicht in: | European journal of haematology 2020-05, Vol.104 (5), p.390-399 |
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| creator | Taneja, Alankrita Kumar, Vivek Chandra, Abhinav B. |
| description | Objective
Primary renal lymphoma (PRL) is defined as a non‐Hodgkin lymphoma (NHL) restricted to kidneys without extensive nodal disease. The literature on epidemiology and outcome in PRL is limited to case reports and small case series.
Methods
We utilized Surveillance, Epidemiology, and End Result database (1984‐2015) to study the demographic, clinical, and pathological characteristics of PRL. We conducted analysis to assess factors associated with overall survival (OS) and cause‐specific survival (CSS).
Results
A total of 599 (0.17% of all NHL) patients were eligible for the study. The age‐adjusted incidence was 0.035/100,000 population and is increasing. The median age was 72 years, and most of the patients were Caucasians and were males. Most of the patients had unilateral tumors, and diffuse large B‐cell lymphoma (DLBCL) was the most common histologic type. The median OS was 112 months, while median CSS was not reached. Age ≥ 60 years was the strongest independent risk factor for worse OS and CSS, while non‐DLBCL histology was associated with better OS and CSS.
Discussion
Primary renal lymphoma is a rare lymphoma with increasing incidence in more recent years. In this study, we describe demographic, clinical, and pathological characteristics of PRL and factors affecting survival among these patients. |
| doi_str_mv | 10.1111/ejh.13360 |
| format | Article |
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Primary renal lymphoma (PRL) is defined as a non‐Hodgkin lymphoma (NHL) restricted to kidneys without extensive nodal disease. The literature on epidemiology and outcome in PRL is limited to case reports and small case series.
Methods
We utilized Surveillance, Epidemiology, and End Result database (1984‐2015) to study the demographic, clinical, and pathological characteristics of PRL. We conducted analysis to assess factors associated with overall survival (OS) and cause‐specific survival (CSS).
Results
A total of 599 (0.17% of all NHL) patients were eligible for the study. The age‐adjusted incidence was 0.035/100,000 population and is increasing. The median age was 72 years, and most of the patients were Caucasians and were males. Most of the patients had unilateral tumors, and diffuse large B‐cell lymphoma (DLBCL) was the most common histologic type. The median OS was 112 months, while median CSS was not reached. Age ≥ 60 years was the strongest independent risk factor for worse OS and CSS, while non‐DLBCL histology was associated with better OS and CSS.
Discussion
Primary renal lymphoma is a rare lymphoma with increasing incidence in more recent years. In this study, we describe demographic, clinical, and pathological characteristics of PRL and factors affecting survival among these patients.</description><identifier>ISSN: 0902-4441</identifier><identifier>EISSN: 1600-0609</identifier><identifier>DOI: 10.1111/ejh.13360</identifier><identifier>PMID: 31769538</identifier><language>eng</language><publisher>England: Wiley Subscription Services, Inc</publisher><subject>Adolescent ; Adult ; Age Factors ; Aged ; Aged, 80 and over ; Case reports ; Child ; Child, Preschool ; Epidemiology ; Female ; History, 20th Century ; History, 21st Century ; Humans ; Incidence ; Infant ; Kaplan-Meier Estimate ; Kidney Neoplasms - diagnosis ; Kidney Neoplasms - epidemiology ; Kidney Neoplasms - history ; Kidneys ; Lymphoma ; Lymphoma - diagnosis ; Lymphoma - epidemiology ; Lymphoma - history ; Male ; Middle Aged ; Non-Hodgkin's lymphoma ; non‐hodgkin lymphoma ; Original ; Population Surveillance ; primary lymphoma ; primary renal lymphoma ; Prognosis ; Proportional Hazards Models ; rare lymphomas ; renal lymphoma ; Retrospective Studies ; Risk factors ; SEER Program ; Tumors ; Young Adult</subject><ispartof>European journal of haematology, 2020-05, Vol.104 (5), p.390-399</ispartof><rights>2020 The Authors. published by John Wiley & Sons Ltd</rights><rights>2020 The Authors. European Journal of Haematology published by John Wiley & Sons Ltd.</rights><rights>2020. This article is published under http://creativecommons.org/licenses/by-nc/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4430-5136c43029923d08e6764be61d26b1f6aab19afb5a1139821ee57a7d5afca3783</citedby><cites>FETCH-LOGICAL-c4430-5136c43029923d08e6764be61d26b1f6aab19afb5a1139821ee57a7d5afca3783</cites><orcidid>0000-0002-7231-2623</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fejh.13360$$EPDF$$P50$$Gwiley$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fejh.13360$$EHTML$$P50$$Gwiley$$Hfree_for_read</linktohtml><link.rule.ids>230,314,776,780,881,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31769538$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Taneja, Alankrita</creatorcontrib><creatorcontrib>Kumar, Vivek</creatorcontrib><creatorcontrib>Chandra, Abhinav B.</creatorcontrib><title>Primary renal lymphoma: A population‐based analysis using the SEER program (1973‐2015)</title><title>European journal of haematology</title><addtitle>Eur J Haematol</addtitle><description>Objective
Primary renal lymphoma (PRL) is defined as a non‐Hodgkin lymphoma (NHL) restricted to kidneys without extensive nodal disease. The literature on epidemiology and outcome in PRL is limited to case reports and small case series.
Methods
We utilized Surveillance, Epidemiology, and End Result database (1984‐2015) to study the demographic, clinical, and pathological characteristics of PRL. We conducted analysis to assess factors associated with overall survival (OS) and cause‐specific survival (CSS).
Results
A total of 599 (0.17% of all NHL) patients were eligible for the study. The age‐adjusted incidence was 0.035/100,000 population and is increasing. The median age was 72 years, and most of the patients were Caucasians and were males. Most of the patients had unilateral tumors, and diffuse large B‐cell lymphoma (DLBCL) was the most common histologic type. The median OS was 112 months, while median CSS was not reached. Age ≥ 60 years was the strongest independent risk factor for worse OS and CSS, while non‐DLBCL histology was associated with better OS and CSS.
Discussion
Primary renal lymphoma is a rare lymphoma with increasing incidence in more recent years. In this study, we describe demographic, clinical, and pathological characteristics of PRL and factors affecting survival among these patients.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Age Factors</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Case reports</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Epidemiology</subject><subject>Female</subject><subject>History, 20th Century</subject><subject>History, 21st Century</subject><subject>Humans</subject><subject>Incidence</subject><subject>Infant</subject><subject>Kaplan-Meier Estimate</subject><subject>Kidney Neoplasms - diagnosis</subject><subject>Kidney Neoplasms - epidemiology</subject><subject>Kidney Neoplasms - history</subject><subject>Kidneys</subject><subject>Lymphoma</subject><subject>Lymphoma - diagnosis</subject><subject>Lymphoma - epidemiology</subject><subject>Lymphoma - history</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Non-Hodgkin's lymphoma</subject><subject>non‐hodgkin lymphoma</subject><subject>Original</subject><subject>Population Surveillance</subject><subject>primary lymphoma</subject><subject>primary renal lymphoma</subject><subject>Prognosis</subject><subject>Proportional Hazards Models</subject><subject>rare lymphomas</subject><subject>renal lymphoma</subject><subject>Retrospective Studies</subject><subject>Risk factors</subject><subject>SEER Program</subject><subject>Tumors</subject><subject>Young Adult</subject><issn>0902-4441</issn><issn>1600-0609</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>24P</sourceid><sourceid>EIF</sourceid><recordid>eNp10UFO3DAUBmALFcFAWfQClaVuYBHwsxM77qISQlOgQqKCdsPGekmcmYySOLUnrWbHEXpGTlLTUNRWwhtb8qdf9vsJeQPsGOI6savlMQgh2RaZgWQsYZLpV2TGNONJmqawS_ZCWDHGuAa1Q3YFKKkzkc_I3WffdOg31NseW9puumHpOnxPT-nghrHFdeP6h_ufBQZbUYxmE5pAx9D0C7peWno7n9_QwbuFx44eglYias4gO3pNtmtsgz142vfJ14_zL2cXydX1-eXZ6VVSpqlgSQZClvHAteaiYrmVSqaFlVBxWUAtEQvQWBcZAgidc7A2U6iqDOsShcrFPvkw5Q5j0dmqtP3aY2uG6WPGYWP-vembpVm470ZxiFOAGHD4FODdt9GGtemaUNq2xd66MRguIFdpznId6bv_6MqNPk7lUWmmuJI8i-poUqV3IXhbPz8GmHlszMTGzO_Gon379-uf5Z-KIjiZwI-mtZuXk8z808UU-Qs-95-n</recordid><startdate>202005</startdate><enddate>202005</enddate><creator>Taneja, Alankrita</creator><creator>Kumar, Vivek</creator><creator>Chandra, Abhinav B.</creator><general>Wiley Subscription Services, Inc</general><general>John Wiley and Sons Inc</general><scope>24P</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QG</scope><scope>7T5</scope><scope>7TM</scope><scope>7TO</scope><scope>H94</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-7231-2623</orcidid></search><sort><creationdate>202005</creationdate><title>Primary renal lymphoma: A population‐based analysis using the SEER program (1973‐2015)</title><author>Taneja, Alankrita ; Kumar, Vivek ; Chandra, Abhinav B.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4430-5136c43029923d08e6764be61d26b1f6aab19afb5a1139821ee57a7d5afca3783</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Age Factors</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Case reports</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Epidemiology</topic><topic>Female</topic><topic>History, 20th Century</topic><topic>History, 21st Century</topic><topic>Humans</topic><topic>Incidence</topic><topic>Infant</topic><topic>Kaplan-Meier Estimate</topic><topic>Kidney Neoplasms - diagnosis</topic><topic>Kidney Neoplasms - epidemiology</topic><topic>Kidney Neoplasms - history</topic><topic>Kidneys</topic><topic>Lymphoma</topic><topic>Lymphoma - diagnosis</topic><topic>Lymphoma - epidemiology</topic><topic>Lymphoma - history</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Non-Hodgkin's lymphoma</topic><topic>non‐hodgkin lymphoma</topic><topic>Original</topic><topic>Population Surveillance</topic><topic>primary lymphoma</topic><topic>primary renal lymphoma</topic><topic>Prognosis</topic><topic>Proportional Hazards Models</topic><topic>rare lymphomas</topic><topic>renal lymphoma</topic><topic>Retrospective Studies</topic><topic>Risk factors</topic><topic>SEER Program</topic><topic>Tumors</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Taneja, Alankrita</creatorcontrib><creatorcontrib>Kumar, Vivek</creatorcontrib><creatorcontrib>Chandra, Abhinav B.</creatorcontrib><collection>Wiley-Blackwell Open Access Collection</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Animal Behavior Abstracts</collection><collection>Immunology Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Oncogenes and Growth Factors Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>European journal of haematology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Taneja, Alankrita</au><au>Kumar, Vivek</au><au>Chandra, Abhinav B.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Primary renal lymphoma: A population‐based analysis using the SEER program (1973‐2015)</atitle><jtitle>European journal of haematology</jtitle><addtitle>Eur J Haematol</addtitle><date>2020-05</date><risdate>2020</risdate><volume>104</volume><issue>5</issue><spage>390</spage><epage>399</epage><pages>390-399</pages><issn>0902-4441</issn><eissn>1600-0609</eissn><abstract>Objective
Primary renal lymphoma (PRL) is defined as a non‐Hodgkin lymphoma (NHL) restricted to kidneys without extensive nodal disease. The literature on epidemiology and outcome in PRL is limited to case reports and small case series.
Methods
We utilized Surveillance, Epidemiology, and End Result database (1984‐2015) to study the demographic, clinical, and pathological characteristics of PRL. We conducted analysis to assess factors associated with overall survival (OS) and cause‐specific survival (CSS).
Results
A total of 599 (0.17% of all NHL) patients were eligible for the study. The age‐adjusted incidence was 0.035/100,000 population and is increasing. The median age was 72 years, and most of the patients were Caucasians and were males. Most of the patients had unilateral tumors, and diffuse large B‐cell lymphoma (DLBCL) was the most common histologic type. The median OS was 112 months, while median CSS was not reached. Age ≥ 60 years was the strongest independent risk factor for worse OS and CSS, while non‐DLBCL histology was associated with better OS and CSS.
Discussion
Primary renal lymphoma is a rare lymphoma with increasing incidence in more recent years. In this study, we describe demographic, clinical, and pathological characteristics of PRL and factors affecting survival among these patients.</abstract><cop>England</cop><pub>Wiley Subscription Services, Inc</pub><pmid>31769538</pmid><doi>10.1111/ejh.13360</doi><tpages>10</tpages><orcidid>https://orcid.org/0000-0002-7231-2623</orcidid><oa>free_for_read</oa></addata></record> |
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| subjects | Adolescent Adult Age Factors Aged Aged, 80 and over Case reports Child Child, Preschool Epidemiology Female History, 20th Century History, 21st Century Humans Incidence Infant Kaplan-Meier Estimate Kidney Neoplasms - diagnosis Kidney Neoplasms - epidemiology Kidney Neoplasms - history Kidneys Lymphoma Lymphoma - diagnosis Lymphoma - epidemiology Lymphoma - history Male Middle Aged Non-Hodgkin's lymphoma non‐hodgkin lymphoma Original Population Surveillance primary lymphoma primary renal lymphoma Prognosis Proportional Hazards Models rare lymphomas renal lymphoma Retrospective Studies Risk factors SEER Program Tumors Young Adult |
| title | Primary renal lymphoma: A population‐based analysis using the SEER program (1973‐2015) |
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