A Systematic Review on Transplantation Studies of the Retinal Pigment Epithelium in Animal Models

The retinal pigment epithelium (RPE) and the adjacent light-sensitive photoreceptors form a single functional unit lining the back of the eye. Both cell layers are essential for normal vision. RPE degeneration is usually followed by photoreceptor degeneration and vice versa. There are currently almo...

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Veröffentlicht in:	International journal of molecular sciences 2020-04, Vol.21 (8), p.2719
Hauptverfasser:	Koster, Céline, Wever, Kimberley E, Wagstaff, Ellie L, Hirk, Koen T van den, Hooijmans, Carlijn R, Bergen, Arthur A
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Animal experimentation Animal models Animal research Animals Behavior Bias Cell- and Tissue-Based Therapy Disease Electroretinograms Electroretinography Epithelium Gender Humans Identification methods Lasers Macular degeneration Meta-analysis Models, Animal Morphology Optical Coherence Tomography Photoreceptors Physiological aspects Publication Bias Retina Retinal Degeneration Retinal pigment epithelium Retinal Pigment Epithelium - transplantation Retinitis Retinitis pigmentosa Review Reviews Risk analysis Subgroups Systematic review Thickness Tomography Transplantation Transplants & implants Treatment Outcome Vision
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