BSCI-11. STROMAL PLATELET DERIVED GROWTH FACTOR RECEPTOR-β (PDGFRβ) PROMOTES BREAST CANCER BRAIN METASTASIS
Stromal platelet-derived growth factor receptor-beta (PDGFRβ) has emerged as an actionable mediator of breast tumor-stromal communication. As a receptor tyrosine kinase, PDGFRβ is activated by its ligand, PDGFB, which is released by neighboring tumor epithelium and endothelium. However, how PDGF sig...
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Veröffentlicht in: | Neuro-oncology advances 2019-08, Vol.1 (Supplement_1), p.i3-i3 |
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Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , , |
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Sprache: | eng |
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