Glycine Enhances Satellite Cell Proliferation, Cell Transplantation, and Oligonucleotide Efficacy in Dystrophic Muscle

The need to distribute therapy evenly systemically throughout the large muscle volume within the body makes Duchenne muscular dystrophy (DMD) therapy a challenge. Cell and exon-skipping therapies are promising but have limited effects, and thus enhancing their therapeutic potency is of paramount imp...

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Veröffentlicht in:	Molecular therapy 2020-05, Vol.28 (5), p.1339-1358
Hauptverfasser:	Lin, Caorui, Han, Gang, Ning, Hanhan, Song, Jun, Ran, Ning, Yi, Xianfu, Seow, Yiqi, Yin, HaiFang
Format:	Artikel
Sprache:	eng
Schlagworte:	cell therapy Duchenne muscular dystrophy exon skipping glycine mTORC1 Original satellite cell
Online-Zugang:	Volltext
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