MON-726 Modifications of FOXO1 and GATA4-NKX2.5 Signaling Induce Human Enteroendocrine Differentiation

Enteroendocrine (EE) cells are the most abundant hormone-producing cells in the human body and are vital for metabolism, as well as intestinal and pancreatic function. They have been implicated in the pathogenesis of multiple diseases including diabetes mellitus. Although recent studies have identif...

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Veröffentlicht in:Journal of the Endocrine Society 2020-05, Vol.4 (Supplement_1)
Hauptverfasser: Zeve, Daniel Richard, Stas, Eric, Shah, Manasvi S, Breault, David T
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Sprache:eng
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