Extended Recognition of the Histone H3 Tail by Histone Demethylase KDM5A
Human lysine demethylase KDM5A is a chromatin-modifying enzyme associated with transcriptional regulation, because of its ability to catalyze removal of methyl groups from methylated lysine 4 of histone H3 (H3K4me3). Amplification of KDM5A is observed in many cancers, including breast cancer, prosta...
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| Veröffentlicht in: | Biochemistry (Easton) 2020-02, Vol.59 (5), p.647-651 |
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| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
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