Negligible senescence in naked mole rats may be a consequence of well-maintained splicing regulation

Naked mole-rats (NMRs) have amongst the longest lifespans relative to body size of any known, non-volant mammalian species. They also display an enhanced stress resistance phenotype, negligible senescence and very rarely are they burdened with chronic age-related diseases. Alternative splicing (AS)...

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Veröffentlicht in:	GeroScience 2020-04, Vol.42 (2), p.633-651
Hauptverfasser:	Lee, B. P., Smith, M., Buffenstein, R., Harries, L. W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Aging - genetics Alternative splicing Animals Biomedical and Life Sciences Body size Brain Cell Biology Developmental stages Embryos Geriatrics/Gerontology Life Sciences Life span Longevity - genetics Mice Mole Rats Molecular Medicine Neonates Original Original Article Phenotype Phenotypes RNA Splicing Factors - physiology Senescence Species Spleen Splicing factors Transcription
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