Methylation deficiency disrupts biological rhythms from bacteria to humans

The methyl cycle is a universal metabolic pathway providing methyl groups for the methylation of nuclei acids and proteins, regulating all aspects of cellular physiology. We have previously shown that methyl cycle inhibition in mammals strongly affects circadian rhythms. Since the methyl cycle and c...

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Veröffentlicht in:	Communications biology 2020-05, Vol.3 (1), p.211-211, Article 211
Hauptverfasser:	Fustin, Jean-Michel, Ye, Shiqi, Rakers, Christin, Kaneko, Kensuke, Fukumoto, Kazuki, Yamano, Mayu, Versteven, Marijke, Grünewald, Ellen, Cargill, Samantha J., Tamai, T. Katherine, Xu, Yao, Jabbur, Maria Luísa, Kojima, Rika, Lamberti, Melisa L., Yoshioka-Kobayashi, Kumiko, Whitmore, David, Tammam, Stephanie, Howell, P. Lynne, Kageyama, Ryoichiro, Matsuo, Takuya, Stanewsky, Ralf, Golombek, Diego A., Johnson, Carl Hirschie, Kakeya, Hideaki, van Ooijen, Gerben, Okamura, Hitoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	13/1 13/109 13/44 13/51 14 14/5 38 38/71 38/90 42 59 631/181 631/443/319 631/80/105 64 64/11 64/116 64/24 64/60 82/29 82/58 96 Algae Animals Arabidopsis - physiology Bacteria Biological clocks Biological rhythms Biology Biomedical and Life Sciences Caenorhabditis elegans - physiology Chlamydomonas reinhardtii - physiology Chlorophyta - physiology Circadian Rhythm Circadian rhythms Drosophila melanogaster - physiology Evolution Humans Life Sciences Mammalian cells Mammals Metabolic pathways Methylation Mice - physiology Synechococcus - physiology Therapeutic applications Zebrafish - physiology
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