Homeostatic maintenance and age-related functional decline in the Drosophila ear

Age-related hearing loss (ARHL) is a threat to future human wellbeing. Multiple factors contributing to the terminal auditory decline have been identified; but a unified understanding of ARHL - or the homeostatic maintenance of hearing before its breakdown - is missing. We here present an in-depth a...

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Veröffentlicht in:	Scientific reports 2020-05, Vol.10 (1), p.7431-7431, Article 7431
Hauptverfasser:	Keder, Alyona, Tardieu, Camille, Malong, Liza, Filia, Anastasia, Kashkenbayeva, Assel, Newton, Fay, Georgiades, Marcos, Gale, Jonathan E., Lovett, Michael, Jarman, Andrew P., Albert, Joerg T.
Format:	Artikel
Sprache:	eng
Schlagworte:	631/378 631/378/2619 Aging Animals Arthropod Antennae - physiology Beta2 protein Drosophila Drosophila melanogaster - physiology Drosophila Proteins - genetics Ear Ears & hearing Female Genotype Hearing - genetics Hearing loss Hearing Loss - genetics Homeodomain Proteins - genetics Homeostasis Humanities and Social Sciences Humans Insects Male Math1 protein Mice multidisciplinary Nerve Growth Factors - genetics Nerve Tissue Proteins - genetics Neurons - physiology RNA Interference Science Science (multidisciplinary) Sequence Analysis, RNA SIX gene family Snail protein Sound Time Factors Trans-Activators - genetics Transcription factors Transcription Factors - genetics Transcriptome
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