Antifungal Susceptibility Testing: Current Approaches
Although not as ubiquitous as antibacterial susceptibility testing, antifungal susceptibility testing (AFST) is a tool of increasing importance in clinical microbiology laboratories. The goal of AFST is to reliably produce MIC values that may be used to guide patient therapy, inform epidemiological...
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| Veröffentlicht in: | Clinical microbiology reviews 2020-06, Vol.33 (3) |
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| container_title | Clinical microbiology reviews |
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| creator | Berkow, Elizabeth L Lockhart, Shawn R Ostrosky-Zeichner, Luis |
| description | Although not as ubiquitous as antibacterial susceptibility testing, antifungal susceptibility testing (AFST) is a tool of increasing importance in clinical microbiology laboratories. The goal of AFST is to reliably produce MIC values that may be used to guide patient therapy, inform epidemiological studies, and track rates of antifungal drug resistance. There are three methods that have been standardized by standards development organizations: broth dilution, disk diffusion, and azole agar screening for
Other commonly used methods include gradient diffusion and the use of rapid automated instruments. Novel methodologies for susceptibility testing are in development. It is important for laboratories to consider not only the method of testing but also the interpretation (or lack thereof) of
data. |
| doi_str_mv | 10.1128/cmr.00069-19 |
| format | Article |
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Other commonly used methods include gradient diffusion and the use of rapid automated instruments. Novel methodologies for susceptibility testing are in development. It is important for laboratories to consider not only the method of testing but also the interpretation (or lack thereof) of
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Other commonly used methods include gradient diffusion and the use of rapid automated instruments. Novel methodologies for susceptibility testing are in development. It is important for laboratories to consider not only the method of testing but also the interpretation (or lack thereof) of
data.</description><subject>Antifungal Agents - pharmacology</subject><subject>Aspergillus fumigatus - drug effects</subject><subject>Candida - drug effects</subject><subject>Clinical Laboratory Techniques - methods</subject><subject>Clinical Laboratory Techniques - standards</subject><subject>Drug Resistance, Fungal</subject><subject>Humans</subject><subject>Microbial Sensitivity Tests - methods</subject><subject>Microbial Sensitivity Tests - standards</subject><subject>Mycoses - drug therapy</subject><subject>Mycoses - microbiology</subject><subject>Predictive Value of Tests</subject><subject>Review</subject><issn>0893-8512</issn><issn>1098-6618</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVkM9LwzAUx4Mobk5vnqVHD3bm9aVd4kEYxV8wEXSeQ5qmW6S_TFph_73VTdHTO7wP31-EnAKdAkT8UlduSilNRAhij4yBCh4mCfB9MqZcYMhjiEbkyPs3SoEx5IdkhBEyIQQfk3hed7bo65Uqg5fea9N2NrOl7TbB0vjO1qurIO2dM3UXzNvWNUqvjT8mB4UqvTnZ3Ql5vb1Zpvfh4unuIZ0vQs0EdqFQUW5YEgPFQueAM8yLKNcIRlPUSqiCqiQzTDMQOcZDNm2yKFMxy5UGzHFCrre6bZ9VJtdDCqdK2TpbKbeRjbLy_6e2a7lqPuQMBOOD4ISc7wRc894PhWRlh5JlqWrT9F5GKBIexyhmA3qxRbVrvHem-LUBKr-Wlunjs_xeWoIY8LO_0X7hn2nxE2GQe1o</recordid><startdate>20200617</startdate><enddate>20200617</enddate><creator>Berkow, Elizabeth L</creator><creator>Lockhart, Shawn R</creator><creator>Ostrosky-Zeichner, Luis</creator><general>American Society for Microbiology</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20200617</creationdate><title>Antifungal Susceptibility Testing: Current Approaches</title><author>Berkow, Elizabeth L ; Lockhart, Shawn R ; Ostrosky-Zeichner, Luis</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c493t-9a2de465103fcd1373df2dc31ec03ca9af0a6be4c419d35438ceb2ba54dac13d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Antifungal Agents - pharmacology</topic><topic>Aspergillus fumigatus - drug effects</topic><topic>Candida - drug effects</topic><topic>Clinical Laboratory Techniques - methods</topic><topic>Clinical Laboratory Techniques - standards</topic><topic>Drug Resistance, Fungal</topic><topic>Humans</topic><topic>Microbial Sensitivity Tests - methods</topic><topic>Microbial Sensitivity Tests - standards</topic><topic>Mycoses - drug therapy</topic><topic>Mycoses - microbiology</topic><topic>Predictive Value of Tests</topic><topic>Review</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Berkow, Elizabeth L</creatorcontrib><creatorcontrib>Lockhart, Shawn R</creatorcontrib><creatorcontrib>Ostrosky-Zeichner, Luis</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Clinical microbiology reviews</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Berkow, Elizabeth L</au><au>Lockhart, Shawn R</au><au>Ostrosky-Zeichner, Luis</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Antifungal Susceptibility Testing: Current Approaches</atitle><jtitle>Clinical microbiology reviews</jtitle><addtitle>Clin Microbiol Rev</addtitle><date>2020-06-17</date><risdate>2020</risdate><volume>33</volume><issue>3</issue><issn>0893-8512</issn><eissn>1098-6618</eissn><abstract>Although not as ubiquitous as antibacterial susceptibility testing, antifungal susceptibility testing (AFST) is a tool of increasing importance in clinical microbiology laboratories. The goal of AFST is to reliably produce MIC values that may be used to guide patient therapy, inform epidemiological studies, and track rates of antifungal drug resistance. There are three methods that have been standardized by standards development organizations: broth dilution, disk diffusion, and azole agar screening for
Other commonly used methods include gradient diffusion and the use of rapid automated instruments. Novel methodologies for susceptibility testing are in development. It is important for laboratories to consider not only the method of testing but also the interpretation (or lack thereof) of
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| source | American Society for Microbiology; MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; Alma/SFX Local Collection |
| subjects | Antifungal Agents - pharmacology Aspergillus fumigatus - drug effects Candida - drug effects Clinical Laboratory Techniques - methods Clinical Laboratory Techniques - standards Drug Resistance, Fungal Humans Microbial Sensitivity Tests - methods Microbial Sensitivity Tests - standards Mycoses - drug therapy Mycoses - microbiology Predictive Value of Tests Review |
| title | Antifungal Susceptibility Testing: Current Approaches |
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