The pathogenesis and treatment of the `Cytokine Storm' in COVID-19

Cytokine storm is a general term applied to maladaptive cytokine release in response to infection and other stimuli. The pathogenesis is complex but includes loss of regulatory control of proinflammatory cytokine production, both at local and systemic levels. The disease progresses rapidly, and the...

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Veröffentlicht in:	The Journal of infection 2020-06, Vol.80 (6), p.607-613
Hauptverfasser:	Ye, Qing, Wang, Bili, Mao, Jianhua
Format:	Artikel
Sprache:	eng
Schlagworte:	2019-nCoV Anti-Inflammatory Agents - therapeutic use Betacoronavirus - immunology Coronavirus Coronavirus Infections - complications Coronavirus Infections - physiopathology Coronavirus Infections - therapy COVID-19 Critical Illness - therapy Cytokine Release Syndrome - etiology Cytokine Release Syndrome - physiopathology Cytokine Release Syndrome - therapy Cytokine storm Humans Immunomodulation Pandemics Pneumonia, Viral - complications Pneumonia, Viral - physiopathology Pneumonia, Viral - therapy SARS-CoV-2
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