Homologous recombination and DNA repair mutations in patients treated with carboplatin and nab-paclitaxel for metastatic non-small cell lung cancer

•Chemotherapy remains an important treatment in non-small cell lung cancer.•Patients with homologous recombination mutations had worse survival.•Patients with mutations in DNA repair genes had a trend toward lower response rate. Chemotherapy remains a cornerstone treatment in non-small cell lung can...

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Veröffentlicht in:	Lung cancer (Amsterdam, Netherlands) Netherlands), 2019-08, Vol.134, p.167-173
Hauptverfasser:	Owen, Dwight H., Williams, Terence M., Bertino, Erin M., Mo, Xiaokui, Webb, Amy, Schweitzer, Catherine, Liu, Tom, Roychowdhury, Sameek, Timmers, Cynthia D., Otterson, Gregory A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarker Chemotherapy DNA repair Homologous recombination Non-small cell lung cancer
Online-Zugang:	Volltext
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