Platelet Count and Mean Platelet Volume in Psoriasis Patients

Platelet Count and Mean Platelet Volume in Psoriasis Patients

Psoriasis is a chronic inflammatory, immune-mediated disease, and platelets have an important role in the pathomechanisms of psoriasis. Recent studies showed that MPV (mean platelet volume) could be used as a marker of platelet activation. In this study, we aimed to investigate the MPV level and pla...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Şişli Etfal Hastanesi tıp bülteni 2020-01, Vol.54 (1), p.58-61
Hauptverfasser: Özkur, Ezgi, Şeremet, Sıla, Afşar, Fatma Şule, Altunay, İlknur K, Çalıkoğlu, Emel E
Format: Artikel
Sprache:eng
Schlagworte:
Original Research
Psoriasis
Sedimentation & deposition
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 61
container_issue 1
container_start_page 58
container_title Şişli Etfal Hastanesi tıp bülteni
container_volume 54
creator Özkur, Ezgi
Şeremet, Sıla
Afşar, Fatma Şule
Altunay, İlknur K
Çalıkoğlu, Emel E
description Psoriasis is a chronic inflammatory, immune-mediated disease, and platelets have an important role in the pathomechanisms of psoriasis. Recent studies showed that MPV (mean platelet volume) could be used as a marker of platelet activation. In this study, we aimed to investigate the MPV level and platelet count in psoriasis patients and its association with disease severity. We designed a case-control study with 28 psoriasis patients and age and sex-matched 30 healthy controls. Haematologic parameters and sedimentation rates compared between groups. These parameters also correlated with PASI (Psoriasis Area and Severity Index) score. MPV and platelet count were significantly higher in patients with psoriasis than controls (p=0.012, p=0.015). Also, platelet count was showed positive correlation with PASI scores (r=0.424, p=0.025). The sedimentation rate was not statistically different between groups. There are many conflicting results about the correlation of haematologic parameters and psoriasis. We found that MPV and platelet counts higher in the psoriasis group, which suggests that platelets play an important role in the pathomechanism of psoriasis and may be helpful in assessing treatment outcomes.
doi_str_mv 10.14744/SEMB.2018.69370
format Article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7192260</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2392482638</sourcerecordid><originalsourceid>FETCH-LOGICAL-c354t-fd48711f293d83380e21636e05d93a59f07176bb95c067f6ad4f22551ecbb0943</originalsourceid><addsrcrecordid>eNpdkctLw0AQxhdRrNTePUnAi5fU3Z3NPg4KWuoDWiz4uC6bZKMpSbZmE8H_3qStRZ3LDLPffLPDD6ETgseECcYunqbzmzHFRI65AoH30BEBLMOIUNhf1zQUXT1AI--XuAtOqGDyEA2AghAEoiN0uShMYwvbBBPXVk1gqjSYW1MFu_6rK9rSBnnX8q7Ojc99sDBNbqvGH6ODzBTejrZ5iF5up8-T-3D2ePcwuZ6FCUSsCbOUSUFIRhWkEkBiSwkHbnGUKjCRyrAggsexihLMRcZNyjJKo4jYJI6xYjBEVxvfVRuXNk263bUp9KrOS1N_aWdy_felyt_1m_vUgihKOe4MzrcGtftorW90mfvEFoWprGu9pqCUBEFxLz37J126tq6683oVZZJykJ0Kb1RJ7byvbbb7DMF6jUf3eHSPR6_xdCOnv4_YDfzAgG-IEYk8</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2392482638</pqid></control><display><type>article</type><title>Platelet Count and Mean Platelet Volume in Psoriasis Patients</title><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>PubMed Central</source><source>PubMed Central Open Access</source><creator>Özkur, Ezgi ; Şeremet, Sıla ; Afşar, Fatma Şule ; Altunay, İlknur K ; Çalıkoğlu, Emel E</creator><creatorcontrib>Özkur, Ezgi ; Şeremet, Sıla ; Afşar, Fatma Şule ; Altunay, İlknur K ; Çalıkoğlu, Emel E</creatorcontrib><description>Psoriasis is a chronic inflammatory, immune-mediated disease, and platelets have an important role in the pathomechanisms of psoriasis. Recent studies showed that MPV (mean platelet volume) could be used as a marker of platelet activation. In this study, we aimed to investigate the MPV level and platelet count in psoriasis patients and its association with disease severity. We designed a case-control study with 28 psoriasis patients and age and sex-matched 30 healthy controls. Haematologic parameters and sedimentation rates compared between groups. These parameters also correlated with PASI (Psoriasis Area and Severity Index) score. MPV and platelet count were significantly higher in patients with psoriasis than controls (p=0.012, p=0.015). Also, platelet count was showed positive correlation with PASI scores (r=0.424, p=0.025). The sedimentation rate was not statistically different between groups. There are many conflicting results about the correlation of haematologic parameters and psoriasis. We found that MPV and platelet counts higher in the psoriasis group, which suggests that platelets play an important role in the pathomechanism of psoriasis and may be helpful in assessing treatment outcomes.</description><identifier>ISSN: 1302-7123</identifier><identifier>EISSN: 1308-5123</identifier><identifier>DOI: 10.14744/SEMB.2018.69370</identifier><identifier>PMID: 32377135</identifier><language>eng</language><publisher>Turkey: Kare Publishing</publisher><subject>Original Research ; Psoriasis ; Sedimentation &amp; deposition</subject><ispartof>Şişli Etfal Hastanesi tıp bülteni, 2020-01, Vol.54 (1), p.58-61</ispartof><rights>Copyright: © 2020 by The Medical Bulletin of Sisli Etfal Hospital.</rights><rights>Copyright Yerkure Tanitim ve Yayincilik Hizmetleri A.S. 2020</rights><rights>Copyright: © 2020 by The Medical Bulletin of Sisli Etfal Hospital 2020</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c354t-fd48711f293d83380e21636e05d93a59f07176bb95c067f6ad4f22551ecbb0943</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192260/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192260/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32377135$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Özkur, Ezgi</creatorcontrib><creatorcontrib>Şeremet, Sıla</creatorcontrib><creatorcontrib>Afşar, Fatma Şule</creatorcontrib><creatorcontrib>Altunay, İlknur K</creatorcontrib><creatorcontrib>Çalıkoğlu, Emel E</creatorcontrib><title>Platelet Count and Mean Platelet Volume in Psoriasis Patients</title><title>Şişli Etfal Hastanesi tıp bülteni</title><addtitle>Sisli Etfal Hastan Tip Bul</addtitle><description>Psoriasis is a chronic inflammatory, immune-mediated disease, and platelets have an important role in the pathomechanisms of psoriasis. Recent studies showed that MPV (mean platelet volume) could be used as a marker of platelet activation. In this study, we aimed to investigate the MPV level and platelet count in psoriasis patients and its association with disease severity. We designed a case-control study with 28 psoriasis patients and age and sex-matched 30 healthy controls. Haematologic parameters and sedimentation rates compared between groups. These parameters also correlated with PASI (Psoriasis Area and Severity Index) score. MPV and platelet count were significantly higher in patients with psoriasis than controls (p=0.012, p=0.015). Also, platelet count was showed positive correlation with PASI scores (r=0.424, p=0.025). The sedimentation rate was not statistically different between groups. There are many conflicting results about the correlation of haematologic parameters and psoriasis. We found that MPV and platelet counts higher in the psoriasis group, which suggests that platelets play an important role in the pathomechanism of psoriasis and may be helpful in assessing treatment outcomes.</description><subject>Original Research</subject><subject>Psoriasis</subject><subject>Sedimentation &amp; deposition</subject><issn>1302-7123</issn><issn>1308-5123</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>BENPR</sourceid><recordid>eNpdkctLw0AQxhdRrNTePUnAi5fU3Z3NPg4KWuoDWiz4uC6bZKMpSbZmE8H_3qStRZ3LDLPffLPDD6ETgseECcYunqbzmzHFRI65AoH30BEBLMOIUNhf1zQUXT1AI--XuAtOqGDyEA2AghAEoiN0uShMYwvbBBPXVk1gqjSYW1MFu_6rK9rSBnnX8q7Ojc99sDBNbqvGH6ODzBTejrZ5iF5up8-T-3D2ePcwuZ6FCUSsCbOUSUFIRhWkEkBiSwkHbnGUKjCRyrAggsexihLMRcZNyjJKo4jYJI6xYjBEVxvfVRuXNk263bUp9KrOS1N_aWdy_felyt_1m_vUgihKOe4MzrcGtftorW90mfvEFoWprGu9pqCUBEFxLz37J126tq6683oVZZJykJ0Kb1RJ7byvbbb7DMF6jUf3eHSPR6_xdCOnv4_YDfzAgG-IEYk8</recordid><startdate>20200101</startdate><enddate>20200101</enddate><creator>Özkur, Ezgi</creator><creator>Şeremet, Sıla</creator><creator>Afşar, Fatma Şule</creator><creator>Altunay, İlknur K</creator><creator>Çalıkoğlu, Emel E</creator><general>Kare Publishing</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>EDSIH</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20200101</creationdate><title>Platelet Count and Mean Platelet Volume in Psoriasis Patients</title><author>Özkur, Ezgi ; Şeremet, Sıla ; Afşar, Fatma Şule ; Altunay, İlknur K ; Çalıkoğlu, Emel E</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c354t-fd48711f293d83380e21636e05d93a59f07176bb95c067f6ad4f22551ecbb0943</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Original Research</topic><topic>Psoriasis</topic><topic>Sedimentation &amp; deposition</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Özkur, Ezgi</creatorcontrib><creatorcontrib>Şeremet, Sıla</creatorcontrib><creatorcontrib>Afşar, Fatma Şule</creatorcontrib><creatorcontrib>Altunay, İlknur K</creatorcontrib><creatorcontrib>Çalıkoğlu, Emel E</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Turkey Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Şişli Etfal Hastanesi tıp bülteni</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Özkur, Ezgi</au><au>Şeremet, Sıla</au><au>Afşar, Fatma Şule</au><au>Altunay, İlknur K</au><au>Çalıkoğlu, Emel E</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Platelet Count and Mean Platelet Volume in Psoriasis Patients</atitle><jtitle>Şişli Etfal Hastanesi tıp bülteni</jtitle><addtitle>Sisli Etfal Hastan Tip Bul</addtitle><date>2020-01-01</date><risdate>2020</risdate><volume>54</volume><issue>1</issue><spage>58</spage><epage>61</epage><pages>58-61</pages><issn>1302-7123</issn><eissn>1308-5123</eissn><abstract>Psoriasis is a chronic inflammatory, immune-mediated disease, and platelets have an important role in the pathomechanisms of psoriasis. Recent studies showed that MPV (mean platelet volume) could be used as a marker of platelet activation. In this study, we aimed to investigate the MPV level and platelet count in psoriasis patients and its association with disease severity. We designed a case-control study with 28 psoriasis patients and age and sex-matched 30 healthy controls. Haematologic parameters and sedimentation rates compared between groups. These parameters also correlated with PASI (Psoriasis Area and Severity Index) score. MPV and platelet count were significantly higher in patients with psoriasis than controls (p=0.012, p=0.015). Also, platelet count was showed positive correlation with PASI scores (r=0.424, p=0.025). The sedimentation rate was not statistically different between groups. There are many conflicting results about the correlation of haematologic parameters and psoriasis. We found that MPV and platelet counts higher in the psoriasis group, which suggests that platelets play an important role in the pathomechanism of psoriasis and may be helpful in assessing treatment outcomes.</abstract><cop>Turkey</cop><pub>Kare Publishing</pub><pmid>32377135</pmid><doi>10.14744/SEMB.2018.69370</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 1302-7123
ispartof Şişli Etfal Hastanesi tıp bülteni, 2020-01, Vol.54 (1), p.58-61
issn 1302-7123
1308-5123
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7192260
source Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; PubMed Central Open Access
subjects Original Research
Psoriasis
Sedimentation & deposition
title Platelet Count and Mean Platelet Volume in Psoriasis Patients
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-29T21%3A46%3A35IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Platelet%20Count%20and%20Mean%20Platelet%20Volume%20in%20Psoriasis%20Patients&rft.jtitle=%C5%9Ei%C5%9Fli%20Etfal%20Hastanesi%20t%C4%B1p%20b%C3%BClteni&rft.au=%C3%96zkur,%20Ezgi&rft.date=2020-01-01&rft.volume=54&rft.issue=1&rft.spage=58&rft.epage=61&rft.pages=58-61&rft.issn=1302-7123&rft.eissn=1308-5123&rft_id=info:doi/10.14744/SEMB.2018.69370&rft_dat=%3Cproquest_pubme%3E2392482638%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2392482638&rft_id=info:pmid/32377135&rfr_iscdi=true