Biochemical characterization of SARS-CoV-2 nucleocapsid protein

The nucleocapsid (N) protein is an important antigen for coronavirus, which participate in RNA package and virus particle release. In this study, we expressed the N protein of SARS-CoV-2 and characterized its biochemical properties. Static light scattering, size exclusive chromatography, and small-a...

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Veröffentlicht in:	Biochemical and biophysical research communications 2020-06, Vol.527 (3), p.618-623
Hauptverfasser:	Zeng, Weihong, Liu, Guangfeng, Ma, Huan, Zhao, Dan, Yang, Yunru, Liu, Muziying, Mohammed, Ahmed, Zhao, Changcheng, Yang, Yun, Xie, Jiajia, Ding, Chengchao, Ma, Xiaoling, Weng, Jianping, Gao, Yong, He, Hongliang, Jin, Tengchuan
Format:	Artikel
Sprache:	eng
Schlagworte:	ambient temperature Antibodies, Viral - blood Antigenicity antigens Betacoronavirus - chemistry chromatography Coronavirus Infections COVID-19 COVID-19 infection diagnostic techniques fluorescence Humans immunity Nucleic Acids nucleocapsid Nucleocapsid protein nucleocapsid proteins Nucleocapsid Proteins - chemistry Pandemics Pneumonia, Viral Protein Binding Protein Multimerization Protein Structure, Tertiary RNA packaging SARS-CoV-2 SAXS Scattering, Small Angle Severe acute respiratory syndrome coronavirus 2 small-angle X-ray scattering Structure and function virion X-Ray Diffraction
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