Overexpression of miR-10a-5p facilitates the progression of osteoarthritis

The current study was aimed at exploring the potential roles and possible mechanisms of miR-10a-5p in osteoarthritis (OA). We performed RT-qPCR, Western blot, CCK8, EdU Assay, and flow cytometry assay to clarify the roles of miR-10a-5p in OA. Furthermore, the whole transcriptome sequencing together...

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Veröffentlicht in:	Aging (Albany, NY.) NY.), 2020-04, Vol.12 (7), p.5948-5976
Hauptverfasser:	Li, Hui-Zi, Xu, Xiang-He, Lin, Nan, Wang, Da-Wei, Lin, Yi-Ming, Su, Zhong-Zhen, Lu, Hua-Ding
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Proliferation Computational Biology Disease Progression Gene Expression Profiling - methods Gene Regulatory Networks Homeodomain Proteins - genetics Humans MicroRNAs - genetics Osteoarthritis - genetics Osteoarthritis - physiopathology Pharmacogenetics - methods Research Paper Signal Transduction - genetics Whole Exome Sequencing - methods
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