Human Herpesvirus 6 Detection in Alzheimer’s Disease Cases and Controls across Multiple Cohorts

The interplay between viral infection and Alzheimer’s disease (AD) has long been an area of interest, but proving causality has been elusive. Several recent studies have renewed the debate concerning the role of herpesviruses, and human herpesvirus 6 (HHV-6) in particular, in AD. We screened for HHV...

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Veröffentlicht in:	Neuron (Cambridge, Mass.) Mass.), 2020-03, Vol.105 (6), p.1027-1035.e2
Hauptverfasser:	Allnutt, Mary Alice, Johnson, Kory, Bennett, David A., Connor, Sarah M., Troncoso, Juan C., Pletnikova, Olga, Albert, Marilyn S., Resnick, Susan M., Scholz, Sonja W., De Jager, Philip L., Jacobson, Steven
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer Disease - virology Alzheimer's disease Brain Brain - virology Case-Control Studies Cohort Studies Cytomegalovirus Datasets Dementia Deoxyribonucleic acid Disease DNA DNA sequencing DNA viruses Encephalitis Epstein-Barr virus Female Genetic testing Herpes viruses herpesvirus Herpesvirus 6, Human - genetics Herpesvirus 6, Human - isolation & purification human herpesvirus 6 Humans Infections Male Multiple sclerosis Neurodegenerative diseases Pathogenesis Pathogens Ribonucleic acid RNA Sequence Analysis, DNA - statistics & numerical data Sequence Analysis, RNA - statistics & numerical data Viral infections
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