Genome-Wide Natural Selection Signatures Are Linked to Genetic Risk of Modern Phenotypes in the Japanese Population

Abstract Elucidation of natural selection signatures and relationships with phenotype spectra is important to understand adaptive evolution of modern humans. Here, we conducted a genome-wide scan of selection signatures of the Japanese population by estimating locus-specific time to the most recent...

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Veröffentlicht in:	Molecular biology and evolution 2020-05, Vol.37 (5), p.1306-1316
Hauptverfasser:	Yasumizu, Yoshiaki, Sakaue, Saori, Konuma, Takahiro, Suzuki, Ken, Matsuda, Koichi, Murakami, Yoshinori, Kubo, Michiaki, Palamara, Pier Francesco, Kamatani, Yoichiro, Okada, Yukinori
Format:	Artikel
Sprache:	eng
Schlagworte:	Asian Continental Ancestry Group - genetics Discoveries Genome, Human Genome-Wide Association Study Humans Markov Chains Phenotype Selection, Genetic
Online-Zugang:	Volltext
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