Smooth Muscle Cell Reprogramming in Aortic Aneurysms

The etiology of aortic aneurysms is poorly understood, but it is associated with atherosclerosis, hypercholesterolemia, and abnormal transforming growth factor β (TGF-β) signaling in smooth muscle. Here, we investigated the interactions between these different factors in aortic aneurysm development...

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Veröffentlicht in:	Cell stem cell 2020-04, Vol.26 (4), p.542-557.e11
Hauptverfasser:	Chen, Pei-Yu, Qin, Lingfeng, Li, Guangxin, Malagon-Lopez, Jose, Wang, Zheng, Bergaya, Sonia, Gujja, Sharvari, Caulk, Alexander W, Murtada, Sae-Il, Zhang, Xinbo, Zhuang, Zhen W, Rao, Deepak A, Wang, Guilin, Tobiasova, Zuzana, Jiang, Bo, Montgomery, Ruth R, Sun, Lele, Sun, Hongye, Fisher, Edward A, Gulcher, Jeffrey R, Fernandez-Hernando, Carlos, Humphrey, Jay D, Tellides, George, Chittenden, Thomas W, Simons, Michael
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aorta Aortic Aneurysm Cellular Reprogramming Mice Muscle, Smooth, Vascular Myocytes, Smooth Muscle Transforming Growth Factor beta
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