Molecular Characterization of Tc964, A Novel Antigenic Protein from Trypanosoma cruzi

The Tc964 protein was initially identified by its presence in the interactome associated with the LYT1 mRNAs, which code for a virulence factor of . Tc964 is annotated in the genome as a hypothetical protein. According to phylogenetic analysis, the protein is conserved in the different genera of the...

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Veröffentlicht in:	International journal of molecular sciences 2020-03, Vol.21 (7), p.2432
Hauptverfasser:	Ruiz-Márvez, Elizabeth, Ramírez, César Augusto, Rodríguez, Eliana Rocío, Flórez, Magda Mellisa, Delgado, Gabriela, Guzmán, Fanny, Gómez-Puertas, Paulino, Requena, José María, Puerta, Concepción J
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Animals Antibodies, Protozoan Antigenicity Antigens Antigens, Protozoan - chemistry Antigens, Protozoan - genetics Chagas disease Chagas Disease - diagnosis Chagas Disease - immunology Cross Reactions Cross-reactivity Cutaneous leishmaniasis Dynamic structural analysis Enzymes Epitopes Epitopes, B-Lymphocyte Fractionation Gene expression Genomes GTP Phosphohydrolases Homology Humans Infections Leishmania infantum - genetics Leishmania infantum - metabolism Leishmania major Leishmaniasis - immunology Leishmaniasis, Cutaneous - immunology Leishmaniasis, Cutaneous - parasitology Lymphocytes B Mass spectrometry Molecular dynamics Molecular Dynamics Simulation Parasites Parasitic diseases Peptides Phylogeny Proteins Protozoa Protozoan Proteins - chemistry Protozoan Proteins - genetics Scientific imaging Serologic Tests Simulation Synthetic peptides Tropical diseases Trypanosoma cruzi Trypanosoma cruzi - genetics Trypanosoma cruzi - metabolism Virulence Virulence factors
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