JNK Signaling in Stem Cell Self-Renewal and Differentiation

C-JUN N-terminal kinases (JNKs), which belong to the mitogen-activated protein kinase (MAPK) family, are evolutionarily conserved kinases that mediate cell responses to various types of extracellular stress insults. They regulate physiological processes such as embryonic development and tissue regen...

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Veröffentlicht in:	International journal of molecular sciences 2020-04, Vol.21 (7), p.2613
Hauptverfasser:	Semba, Takashi, Sammons, Rachel, Wang, Xiaoping, Xie, Xuemei, Dalby, Kevin N, Ueno, Naoto T
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis c-Jun protein Cancer therapies Cell cycle Cell death Cell differentiation Cell Differentiation - genetics Cell division Cell proliferation Cell Self Renewal - genetics Cell self-renewal Cell Transformation, Neoplastic - genetics Cell Transformation, Neoplastic - metabolism Differentiation Embryo cells Embryogenesis Gene expression Homeostasis Humans JNK Mitogen-Activated Protein Kinases - metabolism Kinases MAP kinase MAP Kinase Signaling System Metastasis Neoplastic Stem Cells - metabolism Neoplastic Stem Cells - pathology Phenotypes Phosphorylation Pluripotency Protein kinase Regeneration (physiology) Regenerative medicine Review Roles Signal Transduction Stem Cell Niche - genetics Stem cells Stem Cells - cytology Stem Cells - metabolism Tissue engineering Transcription factors Tumor Microenvironment Tumorigenesis
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