IL-1R8 Deficiency Drives Autoimmunity-Associated Lymphoma Development

Chronic inflammation, including that driven by autoimmunity, is associated with development of B-cell lymphomas. IL-1R8 is a regulatory receptor belonging to the IL-1R family, which negatively regulates NF-κB activation following stimulation of IL-1R or Toll Like Receptor (TLR) family members. IL-1R...

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Veröffentlicht in:	Cancer immunology research 2019-04, Vol.7 (6), p.874-885
Hauptverfasser:	Riva, Federica, Ponzoni, Maurilio, Supino, Domenico, Bertilaccio, Maria Teresa Sabrina, Polentarutti, Nadia, Massara, Matteo, Pasqualini, Fabio, Carriero, Roberta, Innocenzi, Anna, Anselmo, Achille, Veliz-Rodriguez, Tania, Simonetti, Giorgia, Anders, Hans-Joachim, Caligaris-Cappio, Federico, Mantovani, Alberto, Muzio, Marta, Garlanda, Cecilia
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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