Ovarian Cancer Incidence in the Multi-Ethnic Asian City-State of Singapore 1968-2012
We investigate ovarian cancer incidence between 1968 and 2012 in Singapore, a multiethnic Asian city state. Aggregated data of ovarian epithelial cancer numbers and estimated person-years from 1968 to 2012 were obtained from Singapore Cancer Registry. Age-Period-Cohort modelling was performed. The a...
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| Veröffentlicht in: | Asian Pacific Journal of Cancer Prevention 2019-12, Vol.20 (12), p.3563-3569 |
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| container_title | Asian Pacific Journal of Cancer Prevention |
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| creator | Hwang, Jeff Yi-Fu Lim, Wei-Yen Tan, Chuen Seng Lim, Sheow Lei Chia, John Chow, Khuan Yew Chay, Wen Yee |
| description | We investigate ovarian cancer incidence between 1968 and 2012 in Singapore, a multiethnic Asian city state.
Aggregated data of ovarian epithelial cancer numbers and estimated person-years from 1968 to 2012 were obtained from Singapore Cancer Registry. Age-Period-Cohort modelling was performed.
The age-standardised incidence rate of ovarian cancer increased from 5.8 to 12.5 per 100,000 per year between 1968 and 2012, while the age-standardised mortality rate has remained stable. This increase was higher among Malays (5.1 to 14.0 per 100,000 per year), compared to Chinese and Indians. Serous carcinoma showed the greatest increase in incidence from 0.4 to 3.4 per 100,000 per year. Period effects were seen in the ovarian cancer incidence trend in Chinese women, but not Malay and Indian women. Clear cell and mucinous carcinoma subtypes were more common in Chinese than in Malay and Indian women. Stage at diagnosis for the years 2003-2010 differed by subtype, and the majority of patients with serous carcinomas presented at a later stage compared to those with clear cell or mucinous carcinomas.
Ovarian cancer incidence rates have doubled in 40 years in Singapore. There were ethnic differences in incidence rates and ovarian cancer subtypes. |
| doi_str_mv | 10.31557/APJCP.2019.20.12.3563 |
| format | Article |
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Aggregated data of ovarian epithelial cancer numbers and estimated person-years from 1968 to 2012 were obtained from Singapore Cancer Registry. Age-Period-Cohort modelling was performed.
The age-standardised incidence rate of ovarian cancer increased from 5.8 to 12.5 per 100,000 per year between 1968 and 2012, while the age-standardised mortality rate has remained stable. This increase was higher among Malays (5.1 to 14.0 per 100,000 per year), compared to Chinese and Indians. Serous carcinoma showed the greatest increase in incidence from 0.4 to 3.4 per 100,000 per year. Period effects were seen in the ovarian cancer incidence trend in Chinese women, but not Malay and Indian women. Clear cell and mucinous carcinoma subtypes were more common in Chinese than in Malay and Indian women. Stage at diagnosis for the years 2003-2010 differed by subtype, and the majority of patients with serous carcinomas presented at a later stage compared to those with clear cell or mucinous carcinomas.
Ovarian cancer incidence rates have doubled in 40 years in Singapore. There were ethnic differences in incidence rates and ovarian cancer subtypes.</description><identifier>ISSN: 2476-762X</identifier><identifier>ISSN: 1513-7368</identifier><identifier>EISSN: 2476-762X</identifier><identifier>DOI: 10.31557/APJCP.2019.20.12.3563</identifier><identifier>PMID: 31870095</identifier><language>eng</language><publisher>Thailand: West Asia Organization for Cancer Prevention</publisher><subject>Adult ; Asian Continental Ancestry Group - statistics & numerical data ; Carcinoma, Ovarian Epithelial - epidemiology ; Carcinoma, Ovarian Epithelial - mortality ; Female ; Humans ; Incidence ; Mortality ; Singapore - epidemiology ; Young Adult</subject><ispartof>Asian Pacific Journal of Cancer Prevention, 2019-12, Vol.20 (12), p.3563-3569</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3293-685362aa1b2e2decd81a86e12c75f0342a2362ff69880b3233c1101bfc274c083</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173386/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173386/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,864,885,27923,27924,53790,53792</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31870095$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hwang, Jeff Yi-Fu</creatorcontrib><creatorcontrib>Lim, Wei-Yen</creatorcontrib><creatorcontrib>Tan, Chuen Seng</creatorcontrib><creatorcontrib>Lim, Sheow Lei</creatorcontrib><creatorcontrib>Chia, John</creatorcontrib><creatorcontrib>Chow, Khuan Yew</creatorcontrib><creatorcontrib>Chay, Wen Yee</creatorcontrib><title>Ovarian Cancer Incidence in the Multi-Ethnic Asian City-State of Singapore 1968-2012</title><title>Asian Pacific Journal of Cancer Prevention</title><addtitle>Asian Pac J Cancer Prev</addtitle><description>We investigate ovarian cancer incidence between 1968 and 2012 in Singapore, a multiethnic Asian city state.
Aggregated data of ovarian epithelial cancer numbers and estimated person-years from 1968 to 2012 were obtained from Singapore Cancer Registry. Age-Period-Cohort modelling was performed.
The age-standardised incidence rate of ovarian cancer increased from 5.8 to 12.5 per 100,000 per year between 1968 and 2012, while the age-standardised mortality rate has remained stable. This increase was higher among Malays (5.1 to 14.0 per 100,000 per year), compared to Chinese and Indians. Serous carcinoma showed the greatest increase in incidence from 0.4 to 3.4 per 100,000 per year. Period effects were seen in the ovarian cancer incidence trend in Chinese women, but not Malay and Indian women. Clear cell and mucinous carcinoma subtypes were more common in Chinese than in Malay and Indian women. Stage at diagnosis for the years 2003-2010 differed by subtype, and the majority of patients with serous carcinomas presented at a later stage compared to those with clear cell or mucinous carcinomas.
Ovarian cancer incidence rates have doubled in 40 years in Singapore. There were ethnic differences in incidence rates and ovarian cancer subtypes.</description><subject>Adult</subject><subject>Asian Continental Ancestry Group - statistics & numerical data</subject><subject>Carcinoma, Ovarian Epithelial - epidemiology</subject><subject>Carcinoma, Ovarian Epithelial - mortality</subject><subject>Female</subject><subject>Humans</subject><subject>Incidence</subject><subject>Mortality</subject><subject>Singapore - epidemiology</subject><subject>Young Adult</subject><issn>2476-762X</issn><issn>1513-7368</issn><issn>2476-762X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVkN1qwkAQhZfSUq3tK8i-QNL9yf7kpiDBWotFQQu9WzabjW7RjWyi4Ns3aiv2ZmbgzDkzfAD0MYopZkw8D2bv2SwmCKdtiTGJKeP0BnRJIngkOPm6vZo74KGuvxFKmBTsHnQolgKhlHXBYrrXwWkPM-2NDXDsjStsO0LnYbOy8GO3blw0bFbeGTioT6uuOUTzRjcWViWcO7_U2ypYiFMuo_Yj8gjuSr2u7dNv74HP1-Eie4sm09E4G0wiQ0lKIy4Z5URrnBNLCmsKibXkFhMjWIloQjRp9bLkqZQop4RSgzHCeWmISAyStAdezrnbXb6xhbG-CXqttsFtdDioSjv1X_FupZbVXgksKJW8DeDnABOqug62vHgxUifO6sRZHTm3RWGijpxbY__68sX2B5b-AH48eF8</recordid><startdate>20191201</startdate><enddate>20191201</enddate><creator>Hwang, Jeff Yi-Fu</creator><creator>Lim, Wei-Yen</creator><creator>Tan, Chuen Seng</creator><creator>Lim, Sheow Lei</creator><creator>Chia, John</creator><creator>Chow, Khuan Yew</creator><creator>Chay, Wen Yee</creator><general>West Asia Organization for Cancer Prevention</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>5PM</scope></search><sort><creationdate>20191201</creationdate><title>Ovarian Cancer Incidence in the Multi-Ethnic Asian City-State of Singapore 1968-2012</title><author>Hwang, Jeff Yi-Fu ; Lim, Wei-Yen ; Tan, Chuen Seng ; Lim, Sheow Lei ; Chia, John ; Chow, Khuan Yew ; Chay, Wen Yee</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3293-685362aa1b2e2decd81a86e12c75f0342a2362ff69880b3233c1101bfc274c083</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Adult</topic><topic>Asian Continental Ancestry Group - statistics & numerical data</topic><topic>Carcinoma, Ovarian Epithelial - epidemiology</topic><topic>Carcinoma, Ovarian Epithelial - mortality</topic><topic>Female</topic><topic>Humans</topic><topic>Incidence</topic><topic>Mortality</topic><topic>Singapore - epidemiology</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hwang, Jeff Yi-Fu</creatorcontrib><creatorcontrib>Lim, Wei-Yen</creatorcontrib><creatorcontrib>Tan, Chuen Seng</creatorcontrib><creatorcontrib>Lim, Sheow Lei</creatorcontrib><creatorcontrib>Chia, John</creatorcontrib><creatorcontrib>Chow, Khuan Yew</creatorcontrib><creatorcontrib>Chay, Wen Yee</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Asian Pacific Journal of Cancer Prevention</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hwang, Jeff Yi-Fu</au><au>Lim, Wei-Yen</au><au>Tan, Chuen Seng</au><au>Lim, Sheow Lei</au><au>Chia, John</au><au>Chow, Khuan Yew</au><au>Chay, Wen Yee</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Ovarian Cancer Incidence in the Multi-Ethnic Asian City-State of Singapore 1968-2012</atitle><jtitle>Asian Pacific Journal of Cancer Prevention</jtitle><addtitle>Asian Pac J Cancer Prev</addtitle><date>2019-12-01</date><risdate>2019</risdate><volume>20</volume><issue>12</issue><spage>3563</spage><epage>3569</epage><pages>3563-3569</pages><issn>2476-762X</issn><issn>1513-7368</issn><eissn>2476-762X</eissn><abstract>We investigate ovarian cancer incidence between 1968 and 2012 in Singapore, a multiethnic Asian city state.
Aggregated data of ovarian epithelial cancer numbers and estimated person-years from 1968 to 2012 were obtained from Singapore Cancer Registry. Age-Period-Cohort modelling was performed.
The age-standardised incidence rate of ovarian cancer increased from 5.8 to 12.5 per 100,000 per year between 1968 and 2012, while the age-standardised mortality rate has remained stable. This increase was higher among Malays (5.1 to 14.0 per 100,000 per year), compared to Chinese and Indians. Serous carcinoma showed the greatest increase in incidence from 0.4 to 3.4 per 100,000 per year. Period effects were seen in the ovarian cancer incidence trend in Chinese women, but not Malay and Indian women. Clear cell and mucinous carcinoma subtypes were more common in Chinese than in Malay and Indian women. Stage at diagnosis for the years 2003-2010 differed by subtype, and the majority of patients with serous carcinomas presented at a later stage compared to those with clear cell or mucinous carcinomas.
Ovarian cancer incidence rates have doubled in 40 years in Singapore. There were ethnic differences in incidence rates and ovarian cancer subtypes.</abstract><cop>Thailand</cop><pub>West Asia Organization for Cancer Prevention</pub><pmid>31870095</pmid><doi>10.31557/APJCP.2019.20.12.3563</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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| language | eng |
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| source | PubMed (Medline); MEDLINE; DOAJ Directory of Open Access Journals; Free E- Journals; EZB Electronic Journals Library |
| subjects | Adult Asian Continental Ancestry Group - statistics & numerical data Carcinoma, Ovarian Epithelial - epidemiology Carcinoma, Ovarian Epithelial - mortality Female Humans Incidence Mortality Singapore - epidemiology Young Adult |
| title | Ovarian Cancer Incidence in the Multi-Ethnic Asian City-State of Singapore 1968-2012 |
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