Epidemiological characteristics of coronavirus disease 2019 (COVID-19) patients in IRAN: A single center study
•The majority of cases were in the age group of 50–60 years of old.•A total of 2964 cases of COVID-19 were investigated.•The male-to-female ratio was 1.93:1.•A significant effect of age, gender and comorbidities on the mortality.•The Case Fatality Rate among understudy cases was 8.06 %. An outbreak...
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| Veröffentlicht in: | Journal of clinical virology 2020-06, Vol.127, p.104378-104378, Article 104378 |
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| creator | Nikpouraghdam, Mohamad Jalali Farahani, Alireza Alishiri, GholamHossein Heydari, Soleyman Ebrahimnia, Mehdi Samadinia, Hossein Sepandi, Mojtaba Jafari, Nematollah Jonaidi Izadi, Morteza Qazvini, Ali Dorostkar, Ruhollah Tat, Mahdi Shahriary, Alireza Farnoosh, Gholamreza Hosseini Zijoud, Seyed Reza Taghdir, Maryam Alimohamadi, Yousef Abbaszadeh, Sepideh Gouvarchin Ghaleh, Hadi Esmaeili Bagheri, Mahdi |
| description | •The majority of cases were in the age group of 50–60 years of old.•A total of 2964 cases of COVID-19 were investigated.•The male-to-female ratio was 1.93:1.•A significant effect of age, gender and comorbidities on the mortality.•The Case Fatality Rate among understudy cases was 8.06 %.
An outbreak of COVID-19 in Iran has spread throughout the country. Identifying the epidemiological characteristics of this disease will help to make appropriate decisions and thus control the epidemic. The aim of this study was characterization of the epidemiological features of COVID-19 in Iran.
In this retrospective study, data related to the epidemiological characteristics of COVID-19 patients admitted to Baqiyatallah Hospital in Tehran, Iran, from 19 February 2020 to 15 April 2020 have been analyzed and reported. Patient characteristics including age, gender and underlying diseases were investigated. Data were collected through patient records. Sex ratio, Case Fatality Rate (CFR) and daily trend of cases were also determined. A multiple logistic regression analysis was also performed to assess affecting factors on mortality.
From February 19, 2020 to April 15, 2020, 12870 patients referred to the hospital emergency department, of which 2968 were hospitalized with COVID-19 diagnosis. The majority of cases were in the age group of 50 to 60 years of old. The male-to-female ratio was 1.93:1. A total of 239 deaths occurred among all cases for an overall CFR of 1.85% based on the total number of patients (both outpatient and inpatient) and 8.06% among hospitalized patients. Out of all patients 10.89% had comorbidity. Diabetes, chronic respiratory diseases, hypertension, cardiovascular diseases, chronic Kidney diseases and cancer were the most common comorbidities with 3.81, 2.02 , 1.99 , 1.25, 0.60 and 0.57 %, respectively. Male gender (OR=1.45, 95% CI: 1.08-1.96), older age (OR=1.05, 95% CI: 1.04-1.06) and having underlying diseases (OR=1.53, 95% CI: 1.04-2.24) were significantly associated with mortality.
The results of this study showed that Male gender, older age and having comorbidities were significantly associated with the risk of death among COVID-19 patients. It is important to pay special attention to male elderly patients with underlying diseases. |
| doi_str_mv | 10.1016/j.jcv.2020.104378 |
| format | Article |
| fullrecord | <record><control><sourceid>pubmed_cross</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7172806</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S1386653220301207</els_id><sourcerecordid>32353762</sourcerecordid><originalsourceid>FETCH-LOGICAL-c517t-aaa4742b4d9af9f677c1370ec9804a69ef820f611a41fa37ef3ba8082bad419d3</originalsourceid><addsrcrecordid>eNp9kE1rGzEQhkVJqfPRH9BL0TE5rKuPXWk3hYBxPmoIMZS2VzGWRo7MemWktcH_PmvchPTS08xo5n018xDyhbMxZ1x9W41XdjcWTBzqUur6AznltZZF1Sh9MuSyVoWqpBiRs5xXjPFKlvoTGUkhK6mVOCXd3SY4XIfYxmWw0FL7DAlsjynkPthMo6c2ptjBLqRtpi5khIxUMN7Qy-n8z-y24M0V3UAfsOszDR2d_Zw8XdMJzaFbtkjt8I6J5n7r9hfko4c24-e_8Zz8vr_7Nf1RPM4fZtPJY2ErrvsCAEpdikXpGvCNV1pbLjVD29SsBNWgrwXzinMouQep0csF1KwWC3Alb5w8JzdH3812sUZ3WCFBazYprCHtTYRg_u104dks485orkXN1GDAjwY2xZwT-jctZ-YA36zMAN8c4Jsj_EHz9f2nb4pX2sPA9-MADqfvAiaT7UDNogsJbW9cDP-xfwEXdZXs</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Epidemiological characteristics of coronavirus disease 2019 (COVID-19) patients in IRAN: A single center study</title><source>MEDLINE</source><source>Access via ScienceDirect (Elsevier)</source><creator>Nikpouraghdam, Mohamad ; Jalali Farahani, Alireza ; Alishiri, GholamHossein ; Heydari, Soleyman ; Ebrahimnia, Mehdi ; Samadinia, Hossein ; Sepandi, Mojtaba ; Jafari, Nematollah Jonaidi ; Izadi, Morteza ; Qazvini, Ali ; Dorostkar, Ruhollah ; Tat, Mahdi ; Shahriary, Alireza ; Farnoosh, Gholamreza ; Hosseini Zijoud, Seyed Reza ; Taghdir, Maryam ; Alimohamadi, Yousef ; Abbaszadeh, Sepideh ; Gouvarchin Ghaleh, Hadi Esmaeili ; Bagheri, Mahdi</creator><creatorcontrib>Nikpouraghdam, Mohamad ; Jalali Farahani, Alireza ; Alishiri, GholamHossein ; Heydari, Soleyman ; Ebrahimnia, Mehdi ; Samadinia, Hossein ; Sepandi, Mojtaba ; Jafari, Nematollah Jonaidi ; Izadi, Morteza ; Qazvini, Ali ; Dorostkar, Ruhollah ; Tat, Mahdi ; Shahriary, Alireza ; Farnoosh, Gholamreza ; Hosseini Zijoud, Seyed Reza ; Taghdir, Maryam ; Alimohamadi, Yousef ; Abbaszadeh, Sepideh ; Gouvarchin Ghaleh, Hadi Esmaeili ; Bagheri, Mahdi</creatorcontrib><description>•The majority of cases were in the age group of 50–60 years of old.•A total of 2964 cases of COVID-19 were investigated.•The male-to-female ratio was 1.93:1.•A significant effect of age, gender and comorbidities on the mortality.•The Case Fatality Rate among understudy cases was 8.06 %.
An outbreak of COVID-19 in Iran has spread throughout the country. Identifying the epidemiological characteristics of this disease will help to make appropriate decisions and thus control the epidemic. The aim of this study was characterization of the epidemiological features of COVID-19 in Iran.
In this retrospective study, data related to the epidemiological characteristics of COVID-19 patients admitted to Baqiyatallah Hospital in Tehran, Iran, from 19 February 2020 to 15 April 2020 have been analyzed and reported. Patient characteristics including age, gender and underlying diseases were investigated. Data were collected through patient records. Sex ratio, Case Fatality Rate (CFR) and daily trend of cases were also determined. A multiple logistic regression analysis was also performed to assess affecting factors on mortality.
From February 19, 2020 to April 15, 2020, 12870 patients referred to the hospital emergency department, of which 2968 were hospitalized with COVID-19 diagnosis. The majority of cases were in the age group of 50 to 60 years of old. The male-to-female ratio was 1.93:1. A total of 239 deaths occurred among all cases for an overall CFR of 1.85% based on the total number of patients (both outpatient and inpatient) and 8.06% among hospitalized patients. Out of all patients 10.89% had comorbidity. Diabetes, chronic respiratory diseases, hypertension, cardiovascular diseases, chronic Kidney diseases and cancer were the most common comorbidities with 3.81, 2.02 , 1.99 , 1.25, 0.60 and 0.57 %, respectively. Male gender (OR=1.45, 95% CI: 1.08-1.96), older age (OR=1.05, 95% CI: 1.04-1.06) and having underlying diseases (OR=1.53, 95% CI: 1.04-2.24) were significantly associated with mortality.
The results of this study showed that Male gender, older age and having comorbidities were significantly associated with the risk of death among COVID-19 patients. It is important to pay special attention to male elderly patients with underlying diseases.</description><identifier>ISSN: 1386-6532</identifier><identifier>EISSN: 1873-5967</identifier><identifier>DOI: 10.1016/j.jcv.2020.104378</identifier><identifier>PMID: 32353762</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>Adolescent ; Adult ; Age Factors ; Aged ; Aged, 80 and over ; Betacoronavirus ; Case Fatality Rate ; Child ; Child, Preschool ; Comorbidity ; Coronavirus Infections - epidemiology ; Coronavirus Infections - mortality ; COVID-19 ; Epidemiology ; Female ; Hospitalization - statistics & numerical data ; Humans ; Infant ; Infant, Newborn ; IRAN ; Iran - epidemiology ; Logistic Models ; Male ; Middle Aged ; Pandemics ; Pneumonia, Viral - epidemiology ; Pneumonia, Viral - mortality ; Retrospective Studies ; Risk Factors ; SARS-CoV-2 ; Sex Factors ; Young Adult</subject><ispartof>Journal of clinical virology, 2020-06, Vol.127, p.104378-104378, Article 104378</ispartof><rights>2020 Elsevier B.V.</rights><rights>Copyright © 2020 Elsevier B.V. All rights reserved.</rights><rights>2020 Elsevier B.V. All rights reserved. 2020 Elsevier B.V.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c517t-aaa4742b4d9af9f677c1370ec9804a69ef820f611a41fa37ef3ba8082bad419d3</citedby><cites>FETCH-LOGICAL-c517t-aaa4742b4d9af9f677c1370ec9804a69ef820f611a41fa37ef3ba8082bad419d3</cites><orcidid>0000-0001-6441-5887</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.jcv.2020.104378$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>230,315,781,785,886,3551,27925,27926,45996</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32353762$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Nikpouraghdam, Mohamad</creatorcontrib><creatorcontrib>Jalali Farahani, Alireza</creatorcontrib><creatorcontrib>Alishiri, GholamHossein</creatorcontrib><creatorcontrib>Heydari, Soleyman</creatorcontrib><creatorcontrib>Ebrahimnia, Mehdi</creatorcontrib><creatorcontrib>Samadinia, Hossein</creatorcontrib><creatorcontrib>Sepandi, Mojtaba</creatorcontrib><creatorcontrib>Jafari, Nematollah Jonaidi</creatorcontrib><creatorcontrib>Izadi, Morteza</creatorcontrib><creatorcontrib>Qazvini, Ali</creatorcontrib><creatorcontrib>Dorostkar, Ruhollah</creatorcontrib><creatorcontrib>Tat, Mahdi</creatorcontrib><creatorcontrib>Shahriary, Alireza</creatorcontrib><creatorcontrib>Farnoosh, Gholamreza</creatorcontrib><creatorcontrib>Hosseini Zijoud, Seyed Reza</creatorcontrib><creatorcontrib>Taghdir, Maryam</creatorcontrib><creatorcontrib>Alimohamadi, Yousef</creatorcontrib><creatorcontrib>Abbaszadeh, Sepideh</creatorcontrib><creatorcontrib>Gouvarchin Ghaleh, Hadi Esmaeili</creatorcontrib><creatorcontrib>Bagheri, Mahdi</creatorcontrib><title>Epidemiological characteristics of coronavirus disease 2019 (COVID-19) patients in IRAN: A single center study</title><title>Journal of clinical virology</title><addtitle>J Clin Virol</addtitle><description>•The majority of cases were in the age group of 50–60 years of old.•A total of 2964 cases of COVID-19 were investigated.•The male-to-female ratio was 1.93:1.•A significant effect of age, gender and comorbidities on the mortality.•The Case Fatality Rate among understudy cases was 8.06 %.
An outbreak of COVID-19 in Iran has spread throughout the country. Identifying the epidemiological characteristics of this disease will help to make appropriate decisions and thus control the epidemic. The aim of this study was characterization of the epidemiological features of COVID-19 in Iran.
In this retrospective study, data related to the epidemiological characteristics of COVID-19 patients admitted to Baqiyatallah Hospital in Tehran, Iran, from 19 February 2020 to 15 April 2020 have been analyzed and reported. Patient characteristics including age, gender and underlying diseases were investigated. Data were collected through patient records. Sex ratio, Case Fatality Rate (CFR) and daily trend of cases were also determined. A multiple logistic regression analysis was also performed to assess affecting factors on mortality.
From February 19, 2020 to April 15, 2020, 12870 patients referred to the hospital emergency department, of which 2968 were hospitalized with COVID-19 diagnosis. The majority of cases were in the age group of 50 to 60 years of old. The male-to-female ratio was 1.93:1. A total of 239 deaths occurred among all cases for an overall CFR of 1.85% based on the total number of patients (both outpatient and inpatient) and 8.06% among hospitalized patients. Out of all patients 10.89% had comorbidity. Diabetes, chronic respiratory diseases, hypertension, cardiovascular diseases, chronic Kidney diseases and cancer were the most common comorbidities with 3.81, 2.02 , 1.99 , 1.25, 0.60 and 0.57 %, respectively. Male gender (OR=1.45, 95% CI: 1.08-1.96), older age (OR=1.05, 95% CI: 1.04-1.06) and having underlying diseases (OR=1.53, 95% CI: 1.04-2.24) were significantly associated with mortality.
The results of this study showed that Male gender, older age and having comorbidities were significantly associated with the risk of death among COVID-19 patients. It is important to pay special attention to male elderly patients with underlying diseases.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Age Factors</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Betacoronavirus</subject><subject>Case Fatality Rate</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Comorbidity</subject><subject>Coronavirus Infections - epidemiology</subject><subject>Coronavirus Infections - mortality</subject><subject>COVID-19</subject><subject>Epidemiology</subject><subject>Female</subject><subject>Hospitalization - statistics & numerical data</subject><subject>Humans</subject><subject>Infant</subject><subject>Infant, Newborn</subject><subject>IRAN</subject><subject>Iran - epidemiology</subject><subject>Logistic Models</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Pandemics</subject><subject>Pneumonia, Viral - epidemiology</subject><subject>Pneumonia, Viral - mortality</subject><subject>Retrospective Studies</subject><subject>Risk Factors</subject><subject>SARS-CoV-2</subject><subject>Sex Factors</subject><subject>Young Adult</subject><issn>1386-6532</issn><issn>1873-5967</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1rGzEQhkVJqfPRH9BL0TE5rKuPXWk3hYBxPmoIMZS2VzGWRo7MemWktcH_PmvchPTS08xo5n018xDyhbMxZ1x9W41XdjcWTBzqUur6AznltZZF1Sh9MuSyVoWqpBiRs5xXjPFKlvoTGUkhK6mVOCXd3SY4XIfYxmWw0FL7DAlsjynkPthMo6c2ptjBLqRtpi5khIxUMN7Qy-n8z-y24M0V3UAfsOszDR2d_Zw8XdMJzaFbtkjt8I6J5n7r9hfko4c24-e_8Zz8vr_7Nf1RPM4fZtPJY2ErrvsCAEpdikXpGvCNV1pbLjVD29SsBNWgrwXzinMouQep0csF1KwWC3Alb5w8JzdH3812sUZ3WCFBazYprCHtTYRg_u104dks485orkXN1GDAjwY2xZwT-jctZ-YA36zMAN8c4Jsj_EHz9f2nb4pX2sPA9-MADqfvAiaT7UDNogsJbW9cDP-xfwEXdZXs</recordid><startdate>20200601</startdate><enddate>20200601</enddate><creator>Nikpouraghdam, Mohamad</creator><creator>Jalali Farahani, Alireza</creator><creator>Alishiri, GholamHossein</creator><creator>Heydari, Soleyman</creator><creator>Ebrahimnia, Mehdi</creator><creator>Samadinia, Hossein</creator><creator>Sepandi, Mojtaba</creator><creator>Jafari, Nematollah Jonaidi</creator><creator>Izadi, Morteza</creator><creator>Qazvini, Ali</creator><creator>Dorostkar, Ruhollah</creator><creator>Tat, Mahdi</creator><creator>Shahriary, Alireza</creator><creator>Farnoosh, Gholamreza</creator><creator>Hosseini Zijoud, Seyed Reza</creator><creator>Taghdir, Maryam</creator><creator>Alimohamadi, Yousef</creator><creator>Abbaszadeh, Sepideh</creator><creator>Gouvarchin Ghaleh, Hadi Esmaeili</creator><creator>Bagheri, Mahdi</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0001-6441-5887</orcidid></search><sort><creationdate>20200601</creationdate><title>Epidemiological characteristics of coronavirus disease 2019 (COVID-19) patients in IRAN: A single center study</title><author>Nikpouraghdam, Mohamad ; Jalali Farahani, Alireza ; Alishiri, GholamHossein ; Heydari, Soleyman ; Ebrahimnia, Mehdi ; Samadinia, Hossein ; Sepandi, Mojtaba ; Jafari, Nematollah Jonaidi ; Izadi, Morteza ; Qazvini, Ali ; Dorostkar, Ruhollah ; Tat, Mahdi ; Shahriary, Alireza ; Farnoosh, Gholamreza ; Hosseini Zijoud, Seyed Reza ; Taghdir, Maryam ; Alimohamadi, Yousef ; Abbaszadeh, Sepideh ; Gouvarchin Ghaleh, Hadi Esmaeili ; Bagheri, Mahdi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c517t-aaa4742b4d9af9f677c1370ec9804a69ef820f611a41fa37ef3ba8082bad419d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Age Factors</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Betacoronavirus</topic><topic>Case Fatality Rate</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Comorbidity</topic><topic>Coronavirus Infections - epidemiology</topic><topic>Coronavirus Infections - mortality</topic><topic>COVID-19</topic><topic>Epidemiology</topic><topic>Female</topic><topic>Hospitalization - statistics & numerical data</topic><topic>Humans</topic><topic>Infant</topic><topic>Infant, Newborn</topic><topic>IRAN</topic><topic>Iran - epidemiology</topic><topic>Logistic Models</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Pandemics</topic><topic>Pneumonia, Viral - epidemiology</topic><topic>Pneumonia, Viral - mortality</topic><topic>Retrospective Studies</topic><topic>Risk Factors</topic><topic>SARS-CoV-2</topic><topic>Sex Factors</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Nikpouraghdam, Mohamad</creatorcontrib><creatorcontrib>Jalali Farahani, Alireza</creatorcontrib><creatorcontrib>Alishiri, GholamHossein</creatorcontrib><creatorcontrib>Heydari, Soleyman</creatorcontrib><creatorcontrib>Ebrahimnia, Mehdi</creatorcontrib><creatorcontrib>Samadinia, Hossein</creatorcontrib><creatorcontrib>Sepandi, Mojtaba</creatorcontrib><creatorcontrib>Jafari, Nematollah Jonaidi</creatorcontrib><creatorcontrib>Izadi, Morteza</creatorcontrib><creatorcontrib>Qazvini, Ali</creatorcontrib><creatorcontrib>Dorostkar, Ruhollah</creatorcontrib><creatorcontrib>Tat, Mahdi</creatorcontrib><creatorcontrib>Shahriary, Alireza</creatorcontrib><creatorcontrib>Farnoosh, Gholamreza</creatorcontrib><creatorcontrib>Hosseini Zijoud, Seyed Reza</creatorcontrib><creatorcontrib>Taghdir, Maryam</creatorcontrib><creatorcontrib>Alimohamadi, Yousef</creatorcontrib><creatorcontrib>Abbaszadeh, Sepideh</creatorcontrib><creatorcontrib>Gouvarchin Ghaleh, Hadi Esmaeili</creatorcontrib><creatorcontrib>Bagheri, Mahdi</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of clinical virology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Nikpouraghdam, Mohamad</au><au>Jalali Farahani, Alireza</au><au>Alishiri, GholamHossein</au><au>Heydari, Soleyman</au><au>Ebrahimnia, Mehdi</au><au>Samadinia, Hossein</au><au>Sepandi, Mojtaba</au><au>Jafari, Nematollah Jonaidi</au><au>Izadi, Morteza</au><au>Qazvini, Ali</au><au>Dorostkar, Ruhollah</au><au>Tat, Mahdi</au><au>Shahriary, Alireza</au><au>Farnoosh, Gholamreza</au><au>Hosseini Zijoud, Seyed Reza</au><au>Taghdir, Maryam</au><au>Alimohamadi, Yousef</au><au>Abbaszadeh, Sepideh</au><au>Gouvarchin Ghaleh, Hadi Esmaeili</au><au>Bagheri, Mahdi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Epidemiological characteristics of coronavirus disease 2019 (COVID-19) patients in IRAN: A single center study</atitle><jtitle>Journal of clinical virology</jtitle><addtitle>J Clin Virol</addtitle><date>2020-06-01</date><risdate>2020</risdate><volume>127</volume><spage>104378</spage><epage>104378</epage><pages>104378-104378</pages><artnum>104378</artnum><issn>1386-6532</issn><eissn>1873-5967</eissn><abstract>•The majority of cases were in the age group of 50–60 years of old.•A total of 2964 cases of COVID-19 were investigated.•The male-to-female ratio was 1.93:1.•A significant effect of age, gender and comorbidities on the mortality.•The Case Fatality Rate among understudy cases was 8.06 %.
An outbreak of COVID-19 in Iran has spread throughout the country. Identifying the epidemiological characteristics of this disease will help to make appropriate decisions and thus control the epidemic. The aim of this study was characterization of the epidemiological features of COVID-19 in Iran.
In this retrospective study, data related to the epidemiological characteristics of COVID-19 patients admitted to Baqiyatallah Hospital in Tehran, Iran, from 19 February 2020 to 15 April 2020 have been analyzed and reported. Patient characteristics including age, gender and underlying diseases were investigated. Data were collected through patient records. Sex ratio, Case Fatality Rate (CFR) and daily trend of cases were also determined. A multiple logistic regression analysis was also performed to assess affecting factors on mortality.
From February 19, 2020 to April 15, 2020, 12870 patients referred to the hospital emergency department, of which 2968 were hospitalized with COVID-19 diagnosis. The majority of cases were in the age group of 50 to 60 years of old. The male-to-female ratio was 1.93:1. A total of 239 deaths occurred among all cases for an overall CFR of 1.85% based on the total number of patients (both outpatient and inpatient) and 8.06% among hospitalized patients. Out of all patients 10.89% had comorbidity. Diabetes, chronic respiratory diseases, hypertension, cardiovascular diseases, chronic Kidney diseases and cancer were the most common comorbidities with 3.81, 2.02 , 1.99 , 1.25, 0.60 and 0.57 %, respectively. Male gender (OR=1.45, 95% CI: 1.08-1.96), older age (OR=1.05, 95% CI: 1.04-1.06) and having underlying diseases (OR=1.53, 95% CI: 1.04-2.24) were significantly associated with mortality.
The results of this study showed that Male gender, older age and having comorbidities were significantly associated with the risk of death among COVID-19 patients. It is important to pay special attention to male elderly patients with underlying diseases.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>32353762</pmid><doi>10.1016/j.jcv.2020.104378</doi><tpages>1</tpages><orcidid>https://orcid.org/0000-0001-6441-5887</orcidid><oa>free_for_read</oa></addata></record> |
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| ispartof | Journal of clinical virology, 2020-06, Vol.127, p.104378-104378, Article 104378 |
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| subjects | Adolescent Adult Age Factors Aged Aged, 80 and over Betacoronavirus Case Fatality Rate Child Child, Preschool Comorbidity Coronavirus Infections - epidemiology Coronavirus Infections - mortality COVID-19 Epidemiology Female Hospitalization - statistics & numerical data Humans Infant Infant, Newborn IRAN Iran - epidemiology Logistic Models Male Middle Aged Pandemics Pneumonia, Viral - epidemiology Pneumonia, Viral - mortality Retrospective Studies Risk Factors SARS-CoV-2 Sex Factors Young Adult |
| title | Epidemiological characteristics of coronavirus disease 2019 (COVID-19) patients in IRAN: A single center study |
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