Acute Flaccid Myelitis: Characteristics and Outcomes of 2014 and 2016 Cases at a Single Center
Acute flaccid myelitis (AFM) is a rare condition associated with spinal cord gray matter abnormalities and frequent persistent motor deficits in the limbs. We present our experience with the diagnosis, management, and outcomes of affected children in 2014 and 2016, emphasizing features that should t...
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| Veröffentlicht in: | The Journal of pediatrics 2019-12, Vol.215, p.272-276.e1 |
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| container_end_page | 276.e1 |
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| container_title | The Journal of pediatrics |
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| creator | Matesanz, Susan McGuire, Jennifer L. Hopkins, Sarah |
| description | Acute flaccid myelitis (AFM) is a rare condition associated with spinal cord gray matter abnormalities and frequent persistent motor deficits in the limbs. We present our experience with the diagnosis, management, and outcomes of affected children in 2014 and 2016, emphasizing features that should trigger early consideration of AFM. Early viral testing may increase the rate of detecting associated viruses. |
| doi_str_mv | 10.1016/j.jpeds.2019.07.015 |
| format | Article |
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We present our experience with the diagnosis, management, and outcomes of affected children in 2014 and 2016, emphasizing features that should trigger early consideration of AFM. 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All rights reserved.</rights><rights>2019 Elsevier Inc. All rights reserved. 2019 Elsevier Inc.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c459t-f8d16f866abd7e7433dc302b6d78855a79e31c385e9ebca5742352fda4ea621f3</citedby><cites>FETCH-LOGICAL-c459t-f8d16f866abd7e7433dc302b6d78855a79e31c385e9ebca5742352fda4ea621f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0022347619308492$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>230,314,776,780,881,3536,27903,27904,65309</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31402137$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Matesanz, Susan</creatorcontrib><creatorcontrib>McGuire, Jennifer L.</creatorcontrib><creatorcontrib>Hopkins, Sarah</creatorcontrib><title>Acute Flaccid Myelitis: Characteristics and Outcomes of 2014 and 2016 Cases at a Single Center</title><title>The Journal of pediatrics</title><addtitle>J Pediatr</addtitle><description>Acute flaccid myelitis (AFM) is a rare condition associated with spinal cord gray matter abnormalities and frequent persistent motor deficits in the limbs. We present our experience with the diagnosis, management, and outcomes of affected children in 2014 and 2016, emphasizing features that should trigger early consideration of AFM. Early viral testing may increase the rate of detecting associated viruses.</description><subject>acute flaccid myelitis</subject><subject>Brain - diagnostic imaging</subject><subject>Central Nervous System Viral Diseases - diagnosis</subject><subject>Central Nervous System Viral Diseases - therapy</subject><subject>Central Nervous System Viral Diseases - virology</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Diagnostic Errors - statistics & numerical data</subject><subject>DNA, Viral</subject><subject>enterovirus</subject><subject>Enterovirus - genetics</subject><subject>Enterovirus - isolation & purification</subject><subject>Female</subject><subject>Fluoxetine - therapeutic use</subject><subject>Glucocorticoids - therapeutic use</subject><subject>Humans</subject><subject>Immunoglobulins, Intravenous - therapeutic use</subject><subject>Infant</subject><subject>Magnetic Resonance Imaging</subject><subject>Male</subject><subject>Methylprednisolone - therapeutic use</subject><subject>myelitis</subject><subject>Myelitis - diagnosis</subject><subject>Myelitis - therapy</subject><subject>Myelitis - virology</subject><subject>Neuromuscular Diseases - diagnosis</subject><subject>Neuromuscular Diseases - therapy</subject><subject>Neuromuscular Diseases - virology</subject><subject>pediatric</subject><subject>Plasma Exchange</subject><subject>Polymerase Chain Reaction</subject><subject>Recovery of Function</subject><subject>Retrospective Studies</subject><subject>Spinal Cord - diagnostic imaging</subject><subject>weakness</subject><issn>0022-3476</issn><issn>1097-6833</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kV1rFDEUhoModm39BYLk0psZTz4mmREUymBVqPSi7a0hm5xps8zOrEmm0H_fdLcWvfEq4eT9OOQh5B2DmgFTHzf1Zoc-1RxYV4OugTUvyIpBpyvVCvGSrAA4r4TU6oi8SWkDAJ0EeE2OBJPAmdAr8uvULRnp2WidC57-vMcx5JA-0f7WRusyxpBycInaydOLJbt5i4nOAy2tcj8sF0V7m8rYZmrpZZhuRqQ9TsV8Ql4Ndkz49uk8JtdnX6_679X5xbcf_el55WTT5WpoPVNDq5Rde41aCuGdAL5WXrdt01jdoWBOtA12uHa20ZKLhg_eSrSKs0Ecky-H3N2y3qJ3pTza0exi2Np4b2YbzL8vU7g1N_Od0UxzBrwEfHgKiPPvBVM225AcjqOdcF6S4VxzzkHupeIgdXFOKeLwXMPAPJIxG7MnYx7JGNCmkCmu939v-Oz5g6IIPh8EWP7pLmA0yQWcHPoQ0WXj5_DfggfQN59w</recordid><startdate>20191201</startdate><enddate>20191201</enddate><creator>Matesanz, Susan</creator><creator>McGuire, Jennifer L.</creator><creator>Hopkins, Sarah</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20191201</creationdate><title>Acute Flaccid Myelitis: Characteristics and Outcomes of 2014 and 2016 Cases at a Single Center</title><author>Matesanz, Susan ; McGuire, Jennifer L. ; Hopkins, Sarah</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c459t-f8d16f866abd7e7433dc302b6d78855a79e31c385e9ebca5742352fda4ea621f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>acute flaccid myelitis</topic><topic>Brain - diagnostic imaging</topic><topic>Central Nervous System Viral Diseases - diagnosis</topic><topic>Central Nervous System Viral Diseases - therapy</topic><topic>Central Nervous System Viral Diseases - virology</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Diagnostic Errors - statistics & numerical data</topic><topic>DNA, Viral</topic><topic>enterovirus</topic><topic>Enterovirus - genetics</topic><topic>Enterovirus - isolation & purification</topic><topic>Female</topic><topic>Fluoxetine - therapeutic use</topic><topic>Glucocorticoids - therapeutic use</topic><topic>Humans</topic><topic>Immunoglobulins, Intravenous - therapeutic use</topic><topic>Infant</topic><topic>Magnetic Resonance Imaging</topic><topic>Male</topic><topic>Methylprednisolone - therapeutic use</topic><topic>myelitis</topic><topic>Myelitis - diagnosis</topic><topic>Myelitis - therapy</topic><topic>Myelitis - virology</topic><topic>Neuromuscular Diseases - diagnosis</topic><topic>Neuromuscular Diseases - therapy</topic><topic>Neuromuscular Diseases - virology</topic><topic>pediatric</topic><topic>Plasma Exchange</topic><topic>Polymerase Chain Reaction</topic><topic>Recovery of Function</topic><topic>Retrospective Studies</topic><topic>Spinal Cord - diagnostic imaging</topic><topic>weakness</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Matesanz, Susan</creatorcontrib><creatorcontrib>McGuire, Jennifer L.</creatorcontrib><creatorcontrib>Hopkins, Sarah</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>The Journal of pediatrics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Matesanz, Susan</au><au>McGuire, Jennifer L.</au><au>Hopkins, Sarah</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Acute Flaccid Myelitis: Characteristics and Outcomes of 2014 and 2016 Cases at a Single Center</atitle><jtitle>The Journal of pediatrics</jtitle><addtitle>J Pediatr</addtitle><date>2019-12-01</date><risdate>2019</risdate><volume>215</volume><spage>272</spage><epage>276.e1</epage><pages>272-276.e1</pages><issn>0022-3476</issn><eissn>1097-6833</eissn><abstract>Acute flaccid myelitis (AFM) is a rare condition associated with spinal cord gray matter abnormalities and frequent persistent motor deficits in the limbs. We present our experience with the diagnosis, management, and outcomes of affected children in 2014 and 2016, emphasizing features that should trigger early consideration of AFM. Early viral testing may increase the rate of detecting associated viruses.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>31402137</pmid><doi>10.1016/j.jpeds.2019.07.015</doi><oa>free_for_read</oa></addata></record> |
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| issn | 0022-3476 1097-6833 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | acute flaccid myelitis Brain - diagnostic imaging Central Nervous System Viral Diseases - diagnosis Central Nervous System Viral Diseases - therapy Central Nervous System Viral Diseases - virology Child Child, Preschool Diagnostic Errors - statistics & numerical data DNA, Viral enterovirus Enterovirus - genetics Enterovirus - isolation & purification Female Fluoxetine - therapeutic use Glucocorticoids - therapeutic use Humans Immunoglobulins, Intravenous - therapeutic use Infant Magnetic Resonance Imaging Male Methylprednisolone - therapeutic use myelitis Myelitis - diagnosis Myelitis - therapy Myelitis - virology Neuromuscular Diseases - diagnosis Neuromuscular Diseases - therapy Neuromuscular Diseases - virology pediatric Plasma Exchange Polymerase Chain Reaction Recovery of Function Retrospective Studies Spinal Cord - diagnostic imaging weakness |
| title | Acute Flaccid Myelitis: Characteristics and Outcomes of 2014 and 2016 Cases at a Single Center |
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