Small molecules targeting viral RNA

Highly conserved noncoding RNA (ncRNA) elements in viral genomes and transcripts offer new opportunities to expand the repertoire of drug targets for the development of antiinfective therapy. Ligands binding to ncRNA architectures are able to affect interactions, structural stability or conformation...

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Bibliographische Detailangaben
Veröffentlicht in:	Wiley interdisciplinary reviews. RNA 2016-11, Vol.7 (6), p.726-743
1. Verfasser:	Hermann, Thomas
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antiviral Agents - pharmacology Coronaviridae Coronaviruses Dengue fever Drug development Ebolavirus Filovirus Genomes Hepatitis C Hepatitis C virus HIV Human immunodeficiency virus Humans Influence of RNA Structure in Biological Systems Influenza Influenza A Influenza A virus Lentivirus Ligands Marburgvirus Non-coding RNA Opinion Orthomyxoviridae Regulatory RNAs Replication Retroviridae Ribonucleic acid Riboswitches RNA RNA viruses RNA, Viral - antagonists & inhibitors RNA, Viral - genetics RNA-mediated interference SARS coronavirus Small Molecule Libraries - pharmacology Small Molecule–RNA Interactions Virus Replication - drug effects Viruses
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