Neutralizing Antibody to Calf Diarrhea Coronavirus in Various Animal Species in Japan

Coronavirus infections associated with respiratory, intestinal or other diseases have been reported in a number of animal species, including man, cattle, pig, dog, cat, mouse, rat, turkey, and chicken. Recently coronaviruses have been divided by immunofluorescence into two distinct groups on the basis of antigenic cross-reactivity, although coronaviruses, as a group, display complex serologic variability. In this paper the authors report on the presence of neutralizing antibodies against calf diarrhea coronavirus in serum specimens from various animal species.