Assessment of blood enterovirus PCR testing in paediatric populations with fever without source, sepsis-like disease, or suspected meningitis: a prospective, multicentre, observational cohort study

Enteroviruses are the most frequent cause of acute meningitis and are seen increasingly in sepsis-like disease and fever without source in the paediatric population. Detection of enterovirus in cerebrospinal fluid (CSF) specimens by PCR is the gold standard diagnostic test. Our aim was to assess a m...

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Veröffentlicht in:	The Lancet infectious diseases 2018-12, Vol.18 (12), p.1385-1396
Hauptverfasser:	Lafolie, Jérémy, Labbé, André, L'Honneur, Anne Sophie, Madhi, Fouad, Pereira, Bruno, Decobert, Marion, Adam, Marie Noelle, Gouraud, François, Faibis, Frédéric, Arditty, Francois, Marque-Juillet, Stéphanie, Guitteny, Marie Aline, Lagathu, Gisele, Verdan, Matthieu, Rozenberg, Flore, Mirand, Audrey, Peigue-Lafeuille, Hélène, Henquell, Cécile, Bailly, Jean-Luc, Archimbaud, Christine, Chacé, Anne, Corlouer, Camille, Mercier, Jean-Christophe, Cotillon, Marie, Magdoud El Alaoui, Fatma, Epaud, Ralph, Nathanson, Sylvie, Coutard, Aymeric, Rochette, Emmanuelle, Brebion, Amélie, Chambon, Martine, Regagnon, Christel, De Pontual, Loic, Carbonnelle, Etienne, Poilane, Isabelle, Benoist, Grégoire, Gault, Elyanne, Millet-Zerner, Véronique, Kuentz, Mathieu, Gallet, Serge, Macchi, Valérie, Ducrocq, Sarah, Epelbaum, Serge, Lambert, Christine, Faye, Albert, Soudée-Mayer, Sophie, Titomanlio, Luigi, Bonacorsi, Stéphane, Cointe, Aurélie, Cloix, Isabelle, Raobison, Aina-Harintsoa, Boutry, Morgane, Tavani, Fabienne
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Age Antibiotics Babies Blood Blood - virology Cerebrospinal fluid Child Child, Preschool Children Cohort analysis Demographics Diagnostic systems Emergency medical services Emergency Service, Hospital Enterovirus Enterovirus - genetics Enterovirus - isolation & purification Enterovirus Infections - diagnosis Enterovirus Infections - virology Family medical history Female Fever Fever of Unknown Origin - diagnosis Fever of Unknown Origin - virology France Human health and pathology Humans Infant Infant, Newborn Infants Infections Infectious diseases Life Sciences Male Meningitis Meningitis - diagnosis Meningitis - virology Molecular Diagnostic Techniques - methods Newborn babies Observational studies Patients Pediatrics Polymerase Chain Reaction - methods Prospective Studies Proteins Santé publique et épidémiologie Sepsis Sepsis - diagnosis Sepsis - virology Studies Tomography Viral infections
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