Comparative pathogenesis of COVID-19, MERS, and SARS in a nonhuman primate model

The current pandemic coronavirus, severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2), was recently identified in patients with an acute respiratory syndrome, coronavirus disease 2019 (COVID-19). To compare its pathogenesis with that of previously emerging coronaviruses, we inoculated cynom...

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Veröffentlicht in:	Science (American Association for the Advancement of Science) 2020-05, Vol.368 (6494), p.1012-1015
Hauptverfasser:	Rockx, Barry, Kuiken, Thijs, Herfst, Sander, Bestebroer, Theo, Lamers, Mart M, Oude Munnink, Bas B, de Meulder, Dennis, van Amerongen, Geert, van den Brand, Judith, Okba, Nisreen M A, Schipper, Debby, van Run, Peter, Leijten, Lonneke, Sikkema, Reina, Verschoor, Ernst, Verstrepen, Babs, Bogers, Willy, Langermans, Jan, Drosten, Christian, Fentener van Vlissingen, Martje, Fouchier, Ron, de Swart, Rik, Koopmans, Marion, Haagmans, Bart L
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Animals Betacoronavirus - isolation & purification Betacoronavirus - pathogenicity Betacoronavirus - physiology Coronavirus Infections - pathology Coronavirus Infections - virology COVID-19 Disease Models, Animal Female Lung - pathology Lung - virology Macaca fascicularis Medicine Microbio Middle East Respiratory Syndrome Coronavirus - isolation & purification Middle East Respiratory Syndrome Coronavirus - physiology Pandemics Pneumonia, Viral - pathology Pneumonia, Viral - virology Pulmonary Alveoli - pathology Pulmonary Alveoli - virology Respiratory System - pathology Respiratory System - virology SARS-CoV-2 Severe Acute Respiratory Syndrome - pathology Severe Acute Respiratory Syndrome - virology Severe acute respiratory syndrome-related coronavirus - isolation & purification Severe acute respiratory syndrome-related coronavirus - physiology Virus Replication Virus Shedding
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