Absolute Improvements in Freedom From Distant Recurrence to Tailor Adjuvant Endocrine Therapies for Premenopausal Women: Results From TEXT and SOFT

The Tamoxifen and Exemestane Trial (TEXT)/Suppression of Ovarian Function Trial (SOFT) showed superior outcomes for premenopausal women with hormone receptor (HR)-positive breast cancer treated with adjuvant exemestane plus ovarian function suppression (OFS) or tamoxifen plus OFS versus tamoxifen al...

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Veröffentlicht in:	Journal of clinical oncology 2020-04, Vol.38 (12), p.1293-1303
Hauptverfasser:	Pagani, Olivia, Francis, Prudence A, Fleming, Gini F, Walley, Barbara A, Viale, Giuseppe, Colleoni, Marco, Láng, István, Gómez, Henry L, Tondini, Carlo, Pinotti, Graziella, Di Leo, Angelo, Coates, Alan S, Goldhirsch, Aron, Gelber, Richard D, Regan, Meredith M
Format:	Artikel
Sprache:	eng
Schlagworte:	Androstadienes - administration & dosage Antineoplastic Agents, Hormonal - administration & dosage Antineoplastic Combined Chemotherapy Protocols - therapeutic use Breast Neoplasms - drug therapy Breast Neoplasms - metabolism Breast Neoplasms - pathology Chemotherapy, Adjuvant Clinical Trials, Phase III as Topic Female Humans Neoplasm Recurrence, Local - pathology Neoplasm Recurrence, Local - prevention & control ORIGINAL REPORTS Ovariectomy Ovary - drug effects Ovary - radiation effects Ovary - surgery Premenopause Randomized Controlled Trials as Topic Receptor, ErbB-2 - metabolism Receptors, Estrogen - metabolism Receptors, Progesterone - metabolism Tamoxifen - administration & dosage Triptorelin Pamoate - administration & dosage
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