Identification of cross‐reactive antibodies for the detection of lymphocytes, myeloid cells and haematopoietic precursors in the naked mole rat

The naked mole rat (Heterocephalus glaber, NMR) is a rodent with exceptional longevity, low rates of age‐related diseases and spontaneous carcinogenesis. The NMR represents an attractive animal model in longevity and cancer research, but there are no NMR‐specific antibodies available to study its im...

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Veröffentlicht in:	European journal of immunology 2019-11, Vol.49 (11), p.2103-2110
Hauptverfasser:	Shebzukhov, Yury, Holtze, Susanne, Hirseland, Heike, Schäfer, Hubert, Radbruch, Andreas, Hildebrandt, Thomas, Grützkau, Andreas
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Animal models Animals Antibodies Antibodies - chemistry Antibodies - isolation & purification B-Lymphocyte Subsets - classification B-Lymphocyte Subsets - cytology B-Lymphocyte Subsets - immunology Biomarkers - analysis Bone composition Bone marrow Bone Marrow Cells - cytology Bone Marrow Cells - immunology Cancer Carcinogenesis Cross Reactions Cytotoxicity Disease Resistance - genetics Disease Resistance - immunology granulocytes Guinea Pigs haematopoietic precursors Hematopoietic Stem Cells - cytology Hematopoietic Stem Cells - immunology Homology Humans Immune system Immunoglobulins Immunology Immunophenotyping Longevity Longevity - genetics Longevity - immunology Lymphocytes Lymphocytes B Lymphocytes T Macrophages Medical research Mice Mole Rats - immunology Monocytes Myeloid cells Myeloid Cells - classification Myeloid Cells - cytology Myeloid Cells - immunology naked mole rat New technology Peripheral blood Short Communication\|Basic Spleen Spleen - cytology Spleen - immunology T-Lymphocyte Subsets - classification T-Lymphocyte Subsets - cytology T-Lymphocyte Subsets - immunology
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