Exosomes from patients with major depression cause depressive-like behaviors in mice with involvement of miR-139-5p-regulated neurogenesis

Exosomal microRNAs (miRNAs) have been suggested to participate in the pathogenesis of neuropsychiatric diseases, but their role in major depressive disorder (MDD) is unknown. We performed a genome-wide miRNA expression profiling of blood-derived exosomes from MDD patients and control subjects and re...

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Veröffentlicht in:Neuropsychopharmacology (New York, N.Y.) N.Y.), 2020-05, Vol.45 (6), p.1050-1058
Hauptverfasser: Wei, Ze-Xu, Xie, Guo-Jun, Mao, Xiao, Zou, Xin-Peng, Liao, Ya-Jin, Liu, Qing-Shan, Wang, Hua, Cheng, Yong
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Sprache:eng
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