Cost-Effectiveness of Personalized Screening for Colorectal Cancer Based on Polygenic Risk and Family History

There is growing evidence for personalizing colorectal cancer screening based on risk factors. We compared the cost-effectiveness of personalized colorectal cancer screening based on polygenic risk and family history to uniform screening. Using the MISCAN-Colon model, we simulated a cohort of 100 mi...

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Veröffentlicht in:	Cancer epidemiology, biomarkers & prevention biomarkers & prevention, 2020-01, Vol.29 (1), p.10-21
Hauptverfasser:	Cenin, Dayna R, Naber, Steffie K, de Weerdt, Anne C, Jenkins, Mark A, Preen, David B, Ee, Hooi C, O'Leary, Peter C, Lansdorp-Vogelaar, Iris
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Australia - epidemiology Colonoscopy - economics Colorectal Neoplasms - diagnosis Colorectal Neoplasms - epidemiology Colorectal Neoplasms - genetics Colorectal Neoplasms - prevention & control Computer Simulation Cost-Benefit Analysis Early Detection of Cancer - economics Early Detection of Cancer - methods Female Genetic Predisposition to Disease Genetic Testing - economics Health Care Costs Humans Male Mass Screening - economics Mass Screening - methods Medical History Taking Middle Aged Models, Economic Multifactorial Inheritance Occult Blood Polymorphism, Single Nucleotide Precision Medicine - economics Precision Medicine - methods Quality-Adjusted Life Years Risk Assessment - economics Risk Assessment - methods Risk Factors
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