Rutin promotes osteogenic differentiation of periodontal ligament stem cells through the GPR30-mediated PI3K/AKT/mTOR signaling pathway

Rutin is one of the flavonoids found in fruits and vegetables. Recent reports have revealed that rutin is a major player in proliferation and bone development. However, data on how rutin regulates the proliferation of periodontal ligament stem cells (PDLSCs), as well as the differentiation of osteog...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Experimental biology and medicine (Maywood, N.J.) N.J.), 2020-03, Vol.245 (6), p.552-561
Hauptverfasser:	Zhao, Bin, Xiong, Yixuan, Zhang, Yunpeng, Jia, Linglu, Zhang, Wenjing, Xu, Xin
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Differentiation Cells, Cultured Chromones - pharmacology Humans Induced Pluripotent Stem Cells - cytology Induced Pluripotent Stem Cells - drug effects Induced Pluripotent Stem Cells - metabolism Morpholines - pharmacology Original Research Osteoblasts - cytology Osteoblasts - drug effects Osteoblasts - metabolism Osteogenesis Periodontal Ligament - cytology Phosphatidylinositol 3-Kinases - metabolism Protein Kinase Inhibitors - pharmacology Proto-Oncogene Proteins c-akt - metabolism Receptors, Estrogen - metabolism Receptors, G-Protein-Coupled - metabolism Rutin - pharmacology Signal Transduction TOR Serine-Threonine Kinases - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!