Does Intensive Treatment Select for Praziquantel Resistance in High-Transmission Settings? Parasitological Trends and Treatment Efficacy Within a Cluster-Randomized Trial

Abstract Background Praziquantel mass drug administration (MDA) is recommended in schistosomiasis-endemic areas. Animal models demonstrate Schistosoma parasite resistance to praziquantel after repeated exposure. Methods We conducted a parasitological survey in 26 fishing communities in Uganda after...

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Veröffentlicht in:	Open Forum Infectious Diseases 2020-04, Vol.7 (4), p.ofaa091-ofaa091
Hauptverfasser:	Tushabe, John Vianney, Lubyayi, Lawrence, Sserubanja, Joel, Kabuubi, Prossy, Abayo, Elson, Kiwanuka, Samuel, Nassuuna, Jacent, Kaweesa, James, Corstjens, Paul, van Dam, Govert, Sanya, Richard E, Ssenyonga, William, Tukahebwa, Edridah Muheki, Kabatereine, Narcis B, Elliott, Alison M, Webb, Emily L
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Clinical trials Drug resistance Fishing Health aspects Major Praziquantel Surveys
Online-Zugang:	Volltext
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