Anti-Osteoarthritic Effects of a Mixture of Dried Pomegranate Concentrate Powder, Eucommiae Cortex, and Achyranthis Radix 5:4:1 ( g / g ) in a Surgically Induced Osteoarthritic Rabbit Model

In this study, we aimed to determine the synergistic effects of a formula consisting of dried pomegranate concentrate powder, Eucommiae Cortex, and Achyranthis Radix 5:4:1 ( / ) (PCP:EC:AR) in a surgically induced osteoarthritis (OA) rabbit model. PCP:EC:AR was orally administered once per day. Knee...

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Veröffentlicht in:	Nutrients 2020-03, Vol.12 (3), p.852
Hauptverfasser:	Choi, Beom-Rak, Kang, Su-Jin, Kim, Jong-Lae, Lee, Young-Joon, Ku, Sae-Kwang
Format:	Artikel
Sprache:	eng
Schlagworte:	Achyranthes Administration, Oral Animals Biomarkers Biomarkers - blood Biomedical materials Cartilage Cartilage diseases Cartilage oligomeric matrix protein Cartilage, Articular - pathology Collagen Collagen (type II) Collagen Type II - blood Cytokines Cytokines - blood Disease Models, Animal Drug dosages Drugs, Chinese Herbal - administration & dosage Eucommiaceae IL-1β Joints (anatomy) Knee Laboratory animals Ligaments Male Matrix metalloproteinase Matrix Metalloproteinase 3 - blood Matrix metalloproteinases Matrix protein Metabolism Metalloproteinase Oral administration Osteoarthritis Osteoarthritis - diagnosis Osteoarthritis - drug therapy Osteoarthritis - pathology Peptide Fragments - blood Phytotherapy Pomegranate Powders Rabbits Rodents Surgery Sutures Synergistic effect Thickness Treatment Outcome Tumor necrosis factor-TNF Tumor necrosis factor-α
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