Genetic responses of inbred chicken lines illustrate importance of eIF2 family and immune-related genes in resistance to Newcastle disease virus

Newcastle disease virus (NDV) replication depends on the translation machinery of the host cell; therefore, the eukaryotic translation initiation factor 2 (eIF2) gene family is a likely candidate for control of viral replication. We hypothesized that differential expression of host genes related to...

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Veröffentlicht in:	Scientific reports 2020-04, Vol.10 (1), p.6155-6155, Article 6155
Hauptverfasser:	Del Vesco, Ana Paula, Kaiser, Michael G., Monson, Melissa S., Zhou, Huaijun, Lamont, Susan J.
Format:	Artikel
Sprache:	eng
Schlagworte:	38/39 631/208/8 631/250/255/2514 Animal sciences Animals Breeding Chickens Chickens - genetics Chickens - immunology Chickens - virology Disease Disease resistance Disease Resistance - genetics Disease Resistance - immunology Eukaryotic Initiation Factor-2 - genetics Eukaryotic Initiation Factor-2 - physiology Gene expression Humanities and Social Sciences Immune response Immunity, Innate - genetics Immunity, Innate - immunology Inbreeding Infections Initiation factor eIF-2 Innate immunity Interferon Kinases multidisciplinary Newcastle disease Newcastle Disease - immunology Newcastle disease virus - immunology Phosphorylation Poultry Protein biosynthesis Protein synthesis Proteins Replication Science Science (multidisciplinary) Signal transduction Spleen Spleen - immunology Spleen - physiopathology Zoology
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