Accurate detection of short and long active ORFs using Ribo-seq data

Abstract Motivation Ribo-seq, a technique for deep-sequencing ribosome-protected mRNA fragments, has enabled transcriptome-wide monitoring of translation in vivo. It has opened avenues for re-evaluating the coding potential of open reading frames (ORFs), including many short ORFs that were previousl...

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Veröffentlicht in:	Bioinformatics 2020-04, Vol.36 (7), p.2053-2059
Hauptverfasser:	Choudhary, Saket, Li, Wenzheng, D. Smith, Andrew
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Humans Mice Open Reading Frames Original Papers Protein Biosynthesis Rats Ribosomes RNA, Messenger Transcriptome
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